Title: Prevalence of Hypothyroidism in Patients with Chronic Kidney Disease in a Tertiary Hospital in South India
Authors: Dr Kaveri Kannan, Dr Preethi Shahila, Dr K.R. Jegan, Dr Parvathy.S
DOI: https://dx.doi.org/10.18535/jmscr/v8i12.41
Abstract
Background: Thyroid hormones have significant impact on kidney disease so it is important to consider the physiological association of thyroid dysfunction in relation to chronic kidney disease (CKD). CKD has been known to affect the pituitary-thyroid axis and the peripheral metabolism of thyroid hormones. Low T3 levels are the most common laboratory finding followed by subclinical hypothyroidism in CKD patients.
Aim: To prove the prevalence of hypothyroidism in CKD patients and its relation between cardiovascular disease and mortality in a tertiary care hospital, in South India.
Materials & Methods: A cross-sectional study was performed among 100 CKD patients of a tertiary care hospital in South India from September 2018 to November 2018 to determine the prevalence of hypothyroidism in the both dialysis dependent and non-dialysis dependent CKD population.
Observation & Conclusion: From this study an increased prevalence of hypothyroidism (clinical and subclinical) was observed in patients with reduced glomerular filtration rate and also an increased risk of cardiovascular events in these patients. Patients in the overt hypothyroid group had increased risk of cardiovascular events compared to euthyroid groups
Keywords: Hypothyroidism, CKD, Cardiovascular events.
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