Thrombotic thrombocytopenic purpura (TTP) is thrombotic microangiopathies, is rare medical condition that occur in pregnancy but if neglected then it will lead to serious maternal and fetal morbidity. TTP clinical findings are similar with preeclampsia, especially the HELLP (Hemolysis, Elevated Liver tests, Low Platelets) syndrome. In this case report patient is known case of TTP in pregnancy, therefore regular ANC visits and timely transfusions of fresh frozen plasma at the interval of 15 days and followed by routine CBC, BLOOD SMEAR, LFT, RFT, LDH done .

TTP in pregnancy is reversible, but life-threatening medical emergency there is need of strict mother and fetal surveillance for the good result, which was done in this case, from 24 wks her first visit till the discharge of the patient as discussed in case report.

Using the regular pentad solely for diagnosis of TTP will lead to underdiagnosis of many cases and should be avoided.

Keywords: TTP, pregnancy.

1. Thompson CE, Damon LE, Ries CA, et al. Thrombotic microangiopathies in the 1980s: clinical features, response to treatment, and the impact of the human immunodeficiency virus epidemic. Blood 1992;80:1890–5. [PubMed] [Google Scholar
2. Martin JN Jr, Bailey AP, Rehberg JF, Owens MT, Keiser SD, May WL. Thrombotic thrombocytopenic purpura in 166 pregnancies: 1955-2006. Am J Obstet Gynecol. 2008;199(2):98–104.
3. Jiang Y, McIntosh JJ, Reese JA, Deford CC, Kremer Hovinga JA, Lammle B, et al. Pregnancy outcomes following recovery from acquired thrombotic thrombocy-topenic purpura. Blood. 2014;123(11): 1674–80.

Dr Neetu Kumari

3rd yr Resident, Umaid Hospital S.N Medical College Jodhpur Rajasthan