Title: To Study Vitamin-D Insufficiency and Deficiency in Patients of Chronic Kidney Disease
Authors: Anand Kumar Singh, Mukesh Kumar Maurya2 Rohit Baiswar, Pratyush Kumar
DOI: https://dx.doi.org/10.18535/jmscr/v8i10.09
Abstract
Background: CKD is an emerging public health problem and one of the most powerful predictors of premature cardiovascular disease. Emerging evidence suggests that the progression of CKD and many of the cardiovascular complications may be linked to hypovitaminosis D. It appears that adequate replacement of vitamin-D in deficiency populations could potentially reduce premature morbidity and mortality.
Objectives: To study prevalence of Vitamin-D insufficiency and deficiency in patients of CKD and its association in different stages of CKD patients.
Methods: A prospective observational study was conducted on 100 patients of CKD attending indoor and outdoor unit in a tertiary care hospital who fulfilled the inclusion criteria.
Results: Suboptimal level of Vitamin-D observed in 90% of the patients with 25(OH) Vitamin-D level < 30 ng/ml in 58% of the patients and Vitamin-D level < 15 ng/ml in 32% of the patients. The proportions of patients with 25(OH) Vitamin-D < 30 ng/ml and < 15 ng/ml by CKD stage were 30% (3 of 10), 46.15% (6 of 13), 54.54% (6 of 11), 70.59% (24 of 34), and 50% (16 of 32), 0, 7.69%(1 of 13), 18.18% (2 of 11), 26.47% (9 of 34) and 50% (16 of 32).
Keywords: Vitamin- D, Chronic Kidney Disease, Insufficiency, Deficiency.
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