Title: Convalescent plasma therapy and COVID-19

Authors: Dr Mital. Patani, Dr Nitin Patani, Dr Angel Espinosa

 DOI: https://dx.doi.org/10.18535/jmscr/v8i9.19

Abstract

COVID-19 is a pandemic outbreak caused by a new coronavirus, SARS-COV-2. Corona infects almost all the countries of the World. Currently, the research on COVID -19 vaccination is still in the empirical stage. COVID is closely related to the original SARS-CoV outbreak in 2003 and convalescent plasma has a very long history of use in the treatment of infectious disease, so based on the previous study on other pandemics viral infectious disease, we try to find evidence to prove the effectiveness of convalescent plasma for the treatment of COVID-19.  Treatment of COVID-19 using the convalescent plasma of recovered COVID-19 donors for the treatment of severe COVID-19 cases could be a better option. The convalescent plasma contains specific IgG and IgM anti–SARS-CoV-19 antibodies, which can neutralize the virus. However, the implementation of a convalescent plasma transfusion program might need comprehensive planning. Concluded that for patient safety, use convalescent plasma therapy along with other symptomatic and clinical treatment as possible as in the early stage of infection.

Keywords: Convalescent plasma (CP), Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

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