Title: Pagets disease Presenting as cardiac failure
Authors: Dr Vishal Venugopal, Dr V.R. Mohan Rao, Dr Vinu Boopathy
DOI: https://dx.doi.org/10.18535/jmscr/v8i8.42
Abstract
Paget’s disease was first described by jamespaget in 1877, It is an archetype of a focal bone disorder with accelerated bone turnover. There is an excessive osteoclastic bone resorption which is followed by compensatory increase in osteoblastic activity, resulting in new bone formation, which is structurally disorganised and more prone for deformities and fractures. Estimated prevalence of Pagets disease in India is around 0.066%.We report a case of 72 year old female presenting with low back ache and hard of hearing, on evaluation she was found to have clinical features of pagets disease complicated by sensorineural deafness and bony deformities.
References
- Franklin Sorneberger, Magnus I smedal, The Mechanism and Incidence of Cardiovascular Changes in Paget's Disease (Osteitis Deformans) A Critical Review of the Literature with Case Studies. doi:doi.org/10.1161/01.CIR.6.5.711
- Kripa elizabethcherian, Nitinkapoor et al, Paget's disease of bone: An entity still exists in India, Indian journal of endocrinology and metabolism
DOI: 10.4103/ijem.IJEM_19_18 - Y. Udayshankar, satyanranjanmishra et al, Paget disease of bone: A classic case report, Contemporary Clinical dentistry, DOI: 10.4103/0976-237X.114858
- Epidemiology and pathology of Paget’s disease of bone –a review Elena Nebot Valenzuela, DOI 10.1007/s10354-016-0496-4
- Bhadada S, Bhansali A, Unnikrishnan AG, Khadgawat R, Singh SK, Mithal A, et al. Does paget’s disease exist in India?: A series of 21 patients. J Assoc Physicians India 2006;54:530‑4.