Title: Nodular Lymphocyte Predominant Hodgkin Lymphoma- A Retrospective Immunohistochemical Study of Patients in Bangalore, Karnataka
Authors: Dr Shankar Anand, Dr Akshatha C, Dr Libin Babu Cherian
DOI: https://dx.doi.org/10.18535/jmscr/v8i8.07
Abstract
Nodular lymphocyte predominant Hodgkin lymphoma comprises 10% of HL and is considered to be an indolent lymphoma, but known for recurrences. Classically seen in middle age population, this lymphoma has a favourable prognosis, unless stage IV ensues, where bone marrow involvement is inevitable and prognosis becomes grim. This study emphasizes on the typical features of NLPHL, with male population being commonly affected. Also the reactive T cell population surrounding the LP cells are consistently positive for CD3 than CD5. LP cells are also positive for CD20, CD79a, CD45, PAX5, OCT-2 and BOB-1 while negative for CD10, CD30 and CD15. The study discusses already known facts of NLPHL with corroboration from previous studies.
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