Majority of mesenchymal neoplasms of gastrointestinal tract are gastrointestinal stromal tumors (GISTs). EGISTs, are the neoplasms which overlaps their histologicaland immunohistological features with those of GISTs, and are found in the abdomen outside of the gastrointestinal tract with no connection to the gastric or intestinal wall. A case of EGIST is reported to show a rare differential diagnosis of an abdominal tumor (arising in abdomen adherent with uterus and appendix in a 66 years old women), emphasizing the proper treatment due to correct diagnosis.

Keywords: Extra gastrointestinal stromal tumors (EGIST), mesenchymal, imatinib.

1. Alkhatib L, Albtoush O, Bataineh N, Gharaibeh K, Matalka I, Tokuda Y. Extra gastrointestinal stromal tumor (EGIST) in the abdominal wall: Case report and literature review. Int J Surg Case Rep 2011;2:253‐
2. H. Yi, B.-B. Park, J. H. Kang et al., “Retrospective analysis of extra-gastrointestinal stromal tumors,” World Journal of Gastroenterology, vol. 21, no. 6, pp. 1845–1850, 2005.
3. Søreide K, Sandvik OM, Søreide JA, Giljaca V, Jureckova A, Bulusu VR. Global epidemiology of gastrointestinal stromal tumours (GIST): A systematic review of population‐based cohort studies. Cancer Epidemiol2016;40:39‐
4. M. Dorfman, M. M. Bui, R. R. Tubbs et al., “The CD117 immunohistochemistry tissue microarray survey for quality assurance and inter laboratory comparison - a College of Amer- ican Pathologists Cell Markers Committee Study,” Archives of pathology & laboratory medicine, vol. 130, no. 6, pp. 779–782, 2006.
5. National Comprehensive Cancer Network, “Soft tissue sarcoma, version 2.2016, NCCN clinical practice guidelines in oncology,” http://www.jnccn.org/content/14/6/758.full.
6. Liegl‐Atzwanger B, Fletcher JA, Fletcher CD. Gastrointestinal stromal tumors. Virchows Arch 2010;456:111‐ 

7. Murayama Y, Yamamoto M, Iwasaki R, Miyazaki T, Saji Y, Doi Y, et al. Greater omentum gastrointestinal stromal tumor with PDGFRA‐mutation and hemoperitoneum. World J Gastrointest Oncol 2012;4:119‐
8. Kirby R, Rajasagaram N, Ghusn M. Primary mesenteric gastrointestinal stromal tumour. J Surg Case Rep 2014;2014. pii: Rju050.
9. Peerlinck ID, Irvin TT, Sarsfield PT, Harington JM. GIST (gastro‐intestinal stromal tumour) of the gallbladder: A case report. ActaChirBelg2004;104:107‐
10. Trabelsi A, Yacoub‐Abid LB, Mtimet A, Abdelkrim SB, Hammedi F, Ali AB, et al. Gastrointestinal stromal tumor of the pancreas: A case report and review of the literature. N Am J Med Sci2009;1:324‐
11. Casella C, Villanacci V, D’Adda F, Codazzi M, Salerni B. Primary extra‐gastrointestinal stromal tumor of retroperitoneum. Clin Med Insights Oncol 2012;6:189‐
12. Miettinen, W. El-Rifai, L.Sobin, and J. Lasota, “Evaluationof malignancy and prognosis of gastrointestinal stromal tumors: a review,” Human Pathology, vol. 33, no. 5, pp. 478–483, 2002.
13. Shinomura, K. Kinoshita, S. Tsutsui, and S. Hirota, “Patho- physiology, diagnosis, and treatment of gastrointestinal stromal tumors,” Journal of Gastroenterology, vol. 40, no. 8, pp. 775– 780, 2005.
14. Quezada, F. Acevedo, A. Marambio et al., “Complete patho- logical response to Imatinibmesylate in an extraintestinal gas- trointestinal stromal tumor,” International Journal of Surgery Case Reports, vol. 5, no. 10, pp. 681–685, 2014.

Dr Kapil Mohan Pal (MD Radiotherapy)

Senior Resident, Department of Radiotherapy & Oncology, IGMC Shimla (H.P), India