Title: Analysis of Histopathological Spectrum of Kidney Lesions – An Institutional Autopsy Study of One Year

Authors: Dr Suwarna B Patil, Dr Shriram Chopade, Dr Swarada V Kangate, Dr Manjiri G Khade, Dr Pradeep S Umap, Dr Pradeep Rudra

 DOI: https://dx.doi.org/10.18535/jmscr/v8i6.115

Abstract

Introduction: Autopsy provides an opportunity to uncover the changing patterns of disease in modern era. Chronic Renal Disease is a global health crisis, with an estimated worldwide prevalence of 8 -16%. So the current study is undertaken with the aims to analyze varied spectrum of renal lesions detected on autopsy and to study effect of associated co-morbidities for renal pathology.

Material and Methods: Present retrospective cross sectional study of both Medico-legal and clinical autopsy cases with total of 260 cases was carried out at Tertiary care center during July 2018 to June 2019.Microscopic histopathological examination was done and correlated with clinical details.

Results: We found 105 (40.38%) cases with renal pathologies, while 155 cases (59.61%) showed normal histology, with most commonly affecting 21-30 years of age. Male to female ratio was 1.7:1. Non-glomerular lesions were more common than glomerular.

Conclusion: Present study reveals many renal lesions which produce no functional derangement and are detected for the first time at autopsy.

Keywords: Autopsy, Kidney lesion, Histopathology, Spectrum, Diabetes, Hypertension.

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