Background: Infertility means inability to conceive after one year of regular unprotected intercourse. It is a global health issue with severe psychological effect on couples not having children.

Aim: To find out the clinical patterns and determinant of infertility in couples based on clinical and laboratory finding.

Methods: This is a prospective study carried out in department of Obstetrics and Gynecology of Patna Medical College Hospital, on Patients attending outdoor from January 2019 to December 2019. 300 Women were selected for the study with the diagnosis of infertility and 20 of them were lost to follow up so 280 women were enrolled in this study.

Result: The mean age of women in this study was 28.43± 2.31 years. Maximum women (62.14%) were in age group 20-29 years. The median duration of marriage was 5years (2-9 years). Primary infertility were reported in 172 (61.42%) women and 108(38.57%) women presented with secondary infertility. Female factor deficiency were found in  59.28% cases, 16.08% cases have only male factor, 24.64% having both male and female factor ,whereas 15.24% cases are with unexplained infertility.

Features of polycystic ovaries and ovulatory dysfunction were found in 16% women. Adenexal pathology found in approx 10% cases, Uterine fibroid detected in 24(8.57%)cases and uterine anomaly were found in 10(3.57%). In tubal factor pathology bilateral tubal blockade seen in 20(7.14%) and single tube block were found in 40(14.28%) women. 16.08% male had abnormality in semen examination. The common abnormalities were azoospermia (6.42%) and oligozoospermiia in 4.64% cases.

Conclusion: Primary infertility cases are more common with female factor predominance over male factor. Ovulatory dysfunction, tubal pathology, hormonal imbalance and abnormal semen parameters were main contributing factor for infertility.

Keywords: Infertility, Female factor, Hysterosalpingography, Semen analysis.

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Dr Rajni Priyanka

Senior Resident, Dept. of Obst & Gynae, P.M.C.H, Patna, India