Title: A Rare Presentation of Trauma Induced Rhabdomyosarcoma
Authors: Dr Preeti Rawat, Shruti Chaudhary, Dr Isha Gupta, Varun Upadhyay
DOI: https://dx.doi.org/10.18535/jmscr/v8i5.14
Abstract
Introduction: Orbital rhabdomyosarcoma (RMS) is a highly malignant tumor that originates mainly from mesenchymal tissue. It is considered a rare and highly aggressive malignancy that should be considered in any orbital which rapidly progresses. Delay in diagnosis and inappropriate treatment negatively affects the outcome.
Case Discussion: 5yr/F presented with LE mass since 4 months associated with globe distortion. h/o trauma 2 years back followed by cataract extraction and secondary IOL implantation with trabeculectomy. 6 months later h/o fall leading to IOL explant, hyphema and vitreous hemorrhage. On examination cavity was filled with mass. CT Scan and MRI Orbit suggestive of Retinoblastoma. Histopathology report following enucleation suggestive of Rhabdomyosarcoma Grade III.
Conclusion: Although rare but it has been postulated that RMS may occur following multiple trauma and since it is one of the few life-threatening diseases that present first to an ophthalmologist; therefore prompt diagnosis and treatment is a life-saving issue.
References
- Kodet R, Newton WA Jr, Hamoudi AB, et al. Orbital rhabdomyosarcomas and related tumors in childhood: relationship of morphology to An Intergroup Rhabdomyosarcoma Study. Med Pediatr Oncol. 1997;29:51- 60.
- Wexler LH, Crist WM, Helman LJ. Rhabdomyosarcoma and the undifferentiated sarcomas. In: Pizzo PA, Poplack DG, eds. Principals and Practice of Pediatric Oncology. 4th ed. Philadelphia, Pa: Lippincott Williams & Wilkins;
- Frezzotti R, Hadjistilianou T, Tosi P. Rhabdomyosarcoma of the orbit: clinical and histopathological analysis of a personal series of 19 cases. 1990; 9:307-312.
- Shields JA, Shields CL. Rhabdomyosarcoma: review for the ophthalmologist. Surv Ophthalmol. 2003; 48:39-57.
- Margo CE, Karcioglu ZA. Diagnostic electromicroscopy. In: Karcioglu ZA, ed. Laboratory Diagnosis in Ophthalmology. New York, NY: Macmillan Publishing Co;