Title: The Accuracy of Touch Imprint Cytology of Core Biopsies from Breast Lesions
Authors: Dr Mamta, Dr Rahul Kumar, Dr Radhika Raman
DOI: https://dx.doi.org/10.18535/jmscr/v8i4.09
Abstract
Introduction: Touch imprint cytology is a very simple method of transferring the cells from the tissue core to the slides and evaluating the same under light microscope. Here we use it for the diagnosis of breast lump either it is benign or malignant.
Aims and Objective: To evaluate the efficacy of touch imprint cytology by comparing it with histopathology report.
Material and Method: Core was cut from the exercised lump of 50 patients and touch imprints were received on slides. They were studied under light microscope after fixing it with absolute alcohol. Results were compared with the histopathology report.
Result: 2 Cases showed false negative result and 20 were true positive. The sensitivity was found to be 93 %
Discussion and Summary: Present study showed that touch imprint cytology yield adequate and satisfactory diagnostic material. It can be used at the site of biopsy and timely diagnosis can be done.
References
- Abijeet D. Hire Gouder, Ashok S Godhi, Prakash R Mallur, Basa Vary V. Gogeri, ShriShail Met Gud: Accuracy of intraoperative imprint smears in breast tumors, Indian j surg. 2006, vol. 68, issue 6.
- Amith, Adhya, Ranjan, Mohanthy. Utility of TIC as an adjunct to core needle biopsy of breast lump. Himalaya Cancer Hospitals and research Centre, Bhubaneswar, Odisha, India DOI: 10.5455/jrmds.2016441.2019.
- R. Tribe, 1965. Department of morbid anatomy, Stoke Mandeville Hospital, Aylesbury: cytological diagnosis of breast tumors by the imprint method. J. Clin. Path. 18; 31-39.
- Charles E. Cox MichelineHyacinthe, Ricardo J. Gonzalez, Gary Lyman, Douglas Reintgen, Ni Ni Ku, Marcia S. Miller, Harvey Greenberg and Santo V. Nicosia: Cytologic evaluation of lumpectomy margins in patients with ductal carcinoma in siu: Clinical outcome. Volume 4, Number 8, 1997.
- Carmicheal AR el al: Breast 2004
- Dudgeon LC, Patrick CV. A new method for the rapid microscopical diagnosis of Tumors: With an account of 200 cases so examined. Br J Surg 1927; 25:250.
- Popp et al: 1991: American cancer society vol 67.
- Suen et al, 1978: Role of imprint cytology in intraoperative diagnosis value and limitation J. Clin. Path. 31:328-337.
- K. Lee-Acta Cytological–europepmc.org: The value of imprint cytology in tumor diagnosis.