Due to predominance of infectious diseases and willing to quick recovery of patients, prescribing antibiotics by physicians are increasing rapidly in worldwide. Except this, unscheduled uses of antibiotics by patients and selling by druggist, are now becomes most frequently used drug group in the health sector. Microbial resistance in human bodies is now created global phenomenon due to mishandling of antibiotics. Now a day, inappropriate use of antibiotics has dominated sever pressures, which is highly impervious concerns. The unharmonious use of antibiotics exposes patient’s adverse effects unnecessarily and raises the cost of health care services. Before choosing an antibiotic, it is very much essential to consider whether an antibiotic is necessary or not. The choice of an antibiotic would depend on the etiological agent, antibiotic factors as well as patient’s history. An early assessment of a patient’s response to the initial stage needs to be extremely important to a physician in antibiotics drug uses. Switching from parenteral to oral agents, Availability of oral antibiotic with good pharmacokinetic properties is encouraging to switching from parental to oral agent. Situation permits to oral therapy, is too much less expensive than parenteral. The led time of treatment for many infections is stillun known, but minimum period of treatment has been recommended for some infections. Although no antibiotics is resistance-proof but the judicious use will extend its useful life.

Keywords: Antibiotic, Etiological, Pharmacokinetic, Coherent, Antimicrobial chemotherapy.

1. Cooke D, Salter A], PhilIips 1. Antibiotic misuse, antibiotic policies and information resources. Antimicrob Chemother 1980; 6 : 435-43.
2. Aswapokee N, Vithayapichet S, Heller RP. Pattern of antibiotic use in medical wards of a University Hospital, Bangkok, Thailand. Rev Infect Dis 1990; 12: 136-4
3. Lim VKE, Cheong YM and Suleiman AB (1993) Pattern of antibiotic usage in Malaysian Hospitals. Singapore Med] 34: 525-8.
4. Lim VKE, Cheong YM, Suleiman AB (1994) the use of surgical prophylaxis in seven Malaysian hospitals. Southeast Asian] Trop Med Public Health 24: 698 - 70l. ii
5. World Health Organization (2000) WHO Global principles for the containment of antimicrobial resistance in animals intended for food: Report of a WHO consultation. Geneva.
6. Kyriopoulos J (2014) Introduction to the politics and economy of the medicine. Presentation of NSPC, National School of Public Health, Europe.
7. Kotsiftopoulos C, Kourkouta L, Papageorgiou M (2014) the use of antibiotic medicine. Monograph, Lap Lambert Academic Publishing, Saarbrucken, Germany.
8. Hellenic Centre for Diseases Control and Prevention (HCDCP) (2007) Guidelines for diagnosis and experiential therapy infections, Athens, Greece.
9. http://www.lexigram.gr/lex/omor/
10. Iosifidi H (2013) Relationship of consumption of anti-microbial medicinal products and microbial resistance in a third-hospital hospital. Study of the effect of therapeutic intervention instructions. Aristotle University of Thessaloniki, Thessaloniki, Greece.
11. Partalidou DA (2016) the global phenomenon of antimicrobial resistance. Presentation of a phenomenon. Thesis. Intermediary Program of Postgraduate Studies. Legal and Theological Schools. Department of Medicine-Dentistry. Aristotle University of Thessaloniki, Thessaloniki,
12. Kotsiftopoulos C, Kourkouta L, Papageorgiou M (2014) the use of antibiotic medicine. Monograph, Lap Lambert Academic Publishing, Saarbrucken, Germany.
13. http://www.onmed.gr/ygeia-eidhseis/story/349561/keelpno
14. Giamarelou E (1988) Principles of antimicrobial chemotherapy of infections. Med J 53: 631-636.
15. Pafitou EN (2012) National Strategy of Cyprus for antibiotic resistance. Democracy of Cyprus. Ministry of Health. Nicosia, Greece.
16. Iosifidi H (2013) Relationship of consumption of anti-microbial medicinal products and microbial resistance in a third-hospital hospital. Study of the effect of therapeutic intervention instructions. Aristotle University of Thessaloniki, Thessaloniki, Greece
17. Partalidou DA (2016) The global phenomenon of antimicrobial resistance. Presentation of a phenomenon. Thesis. Intermediary Program of Postgraduate Studies. Legal and Theological Schools. Department of Medicine-Dentistry. Aristotle University of Thessaloniki, Thessaloniki, Greece.
18. Kourkouta L (2016) PolyPharmacy in Elderly. JPPS 103: 1-5.
19. Kourkouta L, Frantzana E, IliadisCh, Monios A (2016) Health Problems of the Elderly. Monograph. Scholar’s Press. Saarbrucken, Germany.
20. Chrysos G (2017) Development of effective hospital-based Antibiotic Stewardship Program. The role of Infectious Disease Specialist. Sci Chronicles 22: 44-50.
21. Droutsa K (2008) Multifarmacy. Athens, Greece.
22. Abriouel H, Omar NB, Molinos AC, López RL, Grande MJ, et al. (2008) Comparative analysis of genetic diversity and incidence of virulence factors and antibiotic resistance among enterococcal populations from raw fruit and vegetable foods, water and soil, and clinical samples. Int J Food Microbiol 123: 38-49.
23. Nathwani D, TilIotson G, Davey P. Sequential antimicrobial therapy - the role of quinolones. AntimicrobChemother 1997; 39: 441-6.
24. Spyrakis X (2006) Principles of public health in drug consumption. Athens, Greece.

Dr R.A.M. Kausarul Islam

Assistant Professor, Orthopedic Surgery Department, NITOR, Dhaka, Bangladesh