Title: Effect of additive magnesium sulphate on spinal block characteristics in pre-eclampsia patients undergoing lower segment caesarean section
Authors: Dr Sateesh Verma, Dr Vijay Bahadur, Dr Jyotsna Agarwal, Dr Shobhna Jafa, Dr Rajni Kapoor
DOI: https://dx.doi.org/10.18535/jmscr/v8i3.21
Abstract
Background and Aims: Spinal anaesthesia is commonly used anaesthetic technique in preeclampsia patients. Adding additive in spinal anaesthesia improves block characteristics as well as prolongs post-operative analgesia. In this study we aimed to evaluate the effect of additive magnesium sulphate on sensory and motor block properties.
Methods: This prospective randomized study was conducted on 60 ASA II /III preeclampsia patients planned for caesarean section. Patients were randomly allocated to two groups and were given the following drugs intrathecally as per group allocation: Group Mg received 9 mg of0.5% bupivacaine heavy(1.8 ml)+ 20 microgram of fentanyl 50µg/ml (0.4ml) + 50mg of 50% MgS04 (0.1 ml). Group NS received 9 mg of 0.5% bupivacaine heavy (1.8 ml) + 20 microgram of fentanyl 50µg/ml (0.4ml) + 0.1 ml Normal Saline. Parameters monitored were sensory, motor block characteristics and postoperative analgesia.
Results: Time to regress sensory block to L1 and postoperative analgesia was longerin group Mg. Time for complete motor recovery were significantly longer in group Mg as compared to group NS. Group Mg taken more time for onset of sensory and motor blockade.
Conclusion: Addition of magnesium sulphate at 50mg dose as adjuvants to intrathecal bupivacaine and fentanyl significantly prolongs period of the sensory and motor blockade. It also gives longer postoperative analgesia in preeclampsia patients undergoing caesarean section.
Keywords: Caesarean section, Spinal anesthesia, NMDA antagonists, Magnesium sulphate, Postoperative analgesia.
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