Background: Concurrent infection with two agents can result in an illness having overlapping symptoms creating a diagnostic confusion for the treating physician. This study attempts to find the current co-infections rates in dengue patients in a tertiary care hospital Eastern Odisha.

Method: Study conducted from July 2018 to June 2019 comprising of 100 dengue seropositive (NS1/IgM/IgG) patients of age >15 years in IMS & SUM Hospital.

Result: In our study 57% were NS1 positive and 28% had IgM positive for Dengue. NS1 and IgM positive in 8% patients, IgM and IgG positive in 3 % of case which indicated secondary cases and 2 cases with all NS1, IgM,IgG for Dengue positive. Out of 100 dengue patients, 39 % patients had co-infections. In which 12% were ICT positive for malaria, 9% salmonella IgM reactive, 8% Scrub typhus IgM reactive, 8% chikungunya IgM reactive, 2% Hepatitis B positive. We have found 2% mixed co-infections in dengue IgM positive patients. In our series in clinical manifestations all case (100%) presented with fever, mylagia (70%), headache (52%), rashes (22%), vomiting (17%), retro orbital pain (12%), abdominal pain (10%), yellowish sclera (4%), oliguria (2%), alter sensorium (2%) and bleeding manifestations (46%) cases. Complications detected hepatopathy (52%), ascites (10%), pleural effusion (8%), pneumonia (7%), splenomegaly (7%) nephropathy (5%), DSS (4%), MODS (4%) and DHS in 20 % of cases.

Conclusion:  Co-infection should always be kept in mind while dealing with cases of dengue fever.This study brings out the incidence of dengue and co-infections and also differentiate concurrent infections.

Keywords: Coinfections, Dengue, malaria, salmonella, Scrub Typhus,  chikungunya.

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Uday Bhanu Rout

Department of Medicine, IMS & SUM Hospital, Siksha “O” Anusandhan, K8, Kalinganagar Bhubaneswar, Odisha, India