Title: Study of Apolipoprotein B and Lipid Profile in the Assessment of Cardiovascular Risk in Cases of Hypothyroidism of North Coastal Andhra Pradesh Region

Authors: Simi Iqbal Md, Prem Kumar G

 DOI: https://dx.doi.org/10.18535/jmscr/v8i2.126

Abstract

   

Introduction: Hypothyroidism is a condition with decreased levels of thyroid hormones and elevated levels of Thyroid stimulating Hormone. Hypercholesterolemia is the characteristic feature of hypothyroidism and is also predisposing factor of atherosclerosis.

Patients and Methods: 50 patients of hypothyroidism and 50 healthy subjects are included in this study.

Results: Serum Total cholesterol, Triglycerides, LDL cholesterol, and Apo B are increased, serum HDL cholesterol are decreased in patients with hypothyroidism.

Conclusion: Hypothyroid patients show dyslipidemic profile and Apo-B is significantly high and they are improved markers for prediction of cardiovascular risk in hypothyroidism.

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