Introduction: Hypertension during pregnancy is a major health problem. It is one of the leading causes of perinatal morbidity and mortality Keeping in view of the severity of this condition, the present study attempts to evaluate the serum levels of thyroid hormones reflecting hormonal changes and activity of serum lactate dehydrogenase, along with serum uric acid measurements in understanding the pathophysiological basis of this condition in cases of hypertensive pregnant women in comparison to normal pregnant women. 

Patients and Methods: 50 pre eclamptic women and 50 normotensive women are included in this study.

Results: Serum Thyroid stimulating hormone (TSH) levels areincreased, T3 and T4 levels are not significant serum LDH and Uric acid are increased in pre-eclampsia.

Conclusion: It is concluded that serum TSH, LDH and Uric acid are reliable and inexpensive markers to predict the severity and outcome of pre-eclampsia.

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Ramya Nemani