Title: Role of Diffusion-Weighted Magnetic Resonance Imaging of Brain in Patients with Neurological Deficits

Authors: Dr Thunga Swathi, Dr Jayanti Musib, Dr Julius N Toppo, Dr Kada Venkataramana

 DOI: https://dx.doi.org/10.18535/jmscr/v8i2.43

Abstract

Background and Objectives: Brain lesion is emerging as a distinct disease entity with significant morbidity. The disease characterized by sudden onset of neurological symptoms. The availability of diffusion-weighted magnetic resonance imaging (DW MRI) has become mandatory for accurate diagnosis as it provides information about the location, extent, and severity of the lesion.

The objectives of the present study are to define the brain lesions in clinically suspected neurological deficits patients with the help of diffusion-weighted magnetic resonance imaging.

Materials and Methods: The present cross-sectional study was conducted in the Department of Radiology, KIMS & RF, Amalapuram, during the period of 2017 to 2019 among 40 clinically suspected patients with neurological deficits. The machine used in this study was PHILIPS achieva, 1.5 tesla MRI. For Diffusion-Weighted b values used were 0 and 1000 s/mm2, and the trace images were obtained by applying the gradients in three orthogonal directions.

Results: A maximum numbers of cases were males. The most frequent presenting complaints were neurological deficits. A maximum numbers of cases were of stroke lesions. All stroke lesions appear hyperintense on DWI and hypointense on ADC.  All tumors ADC was high except epidermoid, pituitary adenoma, and GBM.  All infectious lesions ADC was high except for two cases of encephalitis and one case of multiple tubercular abscesses.

Conclusion and Interpretation: DWI comes to an accurate diagnosis of stroke, tumors, infections, trauma, and demyelinating diseases.

Keywords: Diffusion-weighted Imaging, neurological deficits.

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