Diabetes mellitus is associated with high risk factor in patients with acute myocardial infarction. In the myocardial infarction patients Glycogenphophorylse BB is a sensitive and specific marker.The present study was conducted with this objective to find out the status of GPBB in acute myocardial infarction with and without patients.  For this study we included 64 AMI (33 with diabetes mellitus and 31 without diabetes mellitus) and 64 healthy subjects. AMI diagnosed according to the ACC guideline i.e. clinical symptom chest pain, electrocardiograph monitoring and elevated cardiac biomarker. Cardiac marker GPBB was elevated in all the patients within 1 hour after onset of chest pain but it was more elevated in AMI with diabetic patients as compare to the without diabetic patients and there is no statistically significant difference of GPBB between AMI with diabetic and without diabetic patients. We found the highest mean level of GPBB within 3 hour after onset of chest pain.

Keywords: Diabetes mellitus; Acute myocardial infraction; Glycogen phosphorylase BB.

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Chanchal Garg

PhD. Scholar, G.R. Medical College, Gwalior (M.P.)