Marchiafava bignami disease is rare condition characterized by demyelination of corpus callosum. It is seen most often in patients with chronic alcoholism. It is also seen in non alcoholics, for example in patients with malnutrition and poorly controlled diabetes with dramatic fluctuations in serum glucose. If the underlying cause is alcoholism prognosis is poor. It is a rare case of overall prevalence 250 reported cases worldwide. Here we report such a case of 43 year old male presented with seizures and vomiting diagnosed as marchiafava bignami disease. Patient improved on treatment.

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Kondeti Ganga Bhavani

GSL Medical College, Rajanagaram, Rajahmundry 533296 Andhra Pradesh, India