Title: Morphological and visual acuity outcomes associated with single intravitreal injection of Anti- VEGF versus macular photocoagulation for diabetic macular edema
Authors: Dr Vijay Gupta, Dr Dhan Singh Meena, Dr Uma Meena
DOI: https://dx.doi.org/10.18535/jmscr/v8i1.80
Abstract
Aims & Objective: To compare the morphological and visual acuity outcomes associated with single intravitreal injection of Anti- VEGF versus macular photocoagulation for diabetic macular edema.
Method: A prospective case series descriptive study of 40 patients of diabetic macular edema who underwent macular photocoagulation or anti –VEGF injection. Age, sex, treatment method ,follow up, pre & post treatment were evaluated.
Results: Overall 40 patients (20 in MCP group &20 in Anti VEGF group) of which 24 were males &16 were females. 42.5% patients were in the age group 51-60 years. Follow up duration was 4months. Mean pre- treatment visual acuity in logMAR & CMT in MCP group was 0.309±0.287 & 365.5±290.79µm. and in Anti-VEGF group was 0.423±0.352& 331.2±145.98µm. Mean post-treatment visual acuity in logMAR & CMT in group A was 0.353±0.312 & 358.7±223.62µm.and in group B was 0.509±0.394 & 310.3±57.5µm. The difference between pre-treatment & post –treatment visual acuity in group A was not significant (p =0.151 at 4 month) but in group B it was significant (p<0.05). The difference between pre-treatment & post- treatment CMT in both the groups were significant (p= <0.05).
Conclusion: Both visual acuity & CMT significantly reduced in Anti VEGF group whereas in MCP group only there was reduction in CMT .But there was more reduction in macular thickness in Anti- VEGF group as compared to MCP groups.
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