Title: Ulcerative Collitis: Beyond the Basics and Customary

Authors: Prof Dr Binay Kumar, Dr Surabhi

 DOI: https://dx.doi.org/10.18535/jmscr/v8i1.66

Abstract

Background: Involvement  of  the  upper  gastrointestinal  tract  by  inflammatory  bowel  disease  was  thought  to  be  a  feature  of  Crohn's  disease,  whereas  ulcerative  colitis  was  considered  to  be  limited  to  the  colon. 

Methods: We  studied  7  cases  of  inflammatory  bowel  disease  over  a  period  of  15  months  in  Bhagalpur  district  of  Bihar,  India,  which  involved  the  upper  GI  tract. Patients presenting with typical  symptoms  were  investigated  further.  They  underwent  a  an  array  of  tests  based  on  guidelines  for  confirmatory  diagnosis.

Results: Those  patients  who  had  colonoscopic  findings  suggestive  of  ulcerative  colitis  and  the  diagnosis  of  which  was  reiterated  by  other  confirmatory  tests  were  subjected  to  upper  GI  endoscopy.  The  cases  were  positive  for  fecal  calprotectin  level  and  were  also  pANCA  positive. The  endoscopic  and  histopathological  exam  agreed  to  the  diagnosis  of  ulcerative  colitis  in  the  upper  gastrointestinal  tract.

Conclusion: Patients  with  involvement  of  upper  GI,  against  the  popular  belief  should  have  ulcerative  colitis  in  its  differential  diagnosis.

Keywords: Ulcerative  colitis,  Endoscopy,  Upper  Gastrointestinal  tract,  fecal  calprotectin

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