Title: Role of Fine Needle Aspiration Cytology (FNAC) for the Diagnosis of Metastatic Breast tumors in patients attending in Tertiary Care Hospital, at Muzaffarpur, Bihar
Authors: Dr Ram Ugrah Prasad, Dr Manoj Kumar
DOI: https://dx.doi.org/10.18535/jmscr/v8i1.39
Abstract
Objective: Present study was undertaken to evaluate the role of fine needle aspiration cytology (FNAC) to differentiate the tumors metastatic to the breast from primary breast malignancies.
Material and Methods: A total of 752 suspected cases of breast Pathology were sending from different OPD and IPD to our department for FNAC. After detailed clinical history, clinical examination and relevant routine tests FNAC (fine needle aspiration cytology) of Breast were performed.
Result: Out of 752 suspected cases of breast pathology, a total of 56 (7.4%) cases of malignant lesion were diagnosed by FNAC. Out of 56 breast malignancies, 04 (7.1%) cases were diagnosed as extra mammary metastatic breast tumors. The metastatic tumors included 1 cases of malignant melanoma, 1 case each of hematolymphoid malignancy, adenocarcinoma of the ovary and squamous cell carcinoma (left leg).
Conclusion: FNAC diagnosis of metastasis to the breast is essential in order to avoid unnecessary mastectomy and to ensure appropriate chemotherapy or irradiation treatment.
Keywords: Breast carcinoma, metastasis, FNAC, Extra mammary.
References
- McCrea ES, Johnston C, Haney PI. Metastasis to the breast. Am J Roentgeno11983; 141:685-90.
- Silverman JF, Feldman PS, Covell JL, Frable JW. Fine needle aspiration cytology of neoplasms metastatic to the breast. Acta Cytol 1987; 31:291-300.
- Deshpande AH, Munshi MM, Lele VR, Babhate SK. Aspiration cytology of extramammary tumours metastatic to the breast. Diagn. Cytopathol 1999; 21:319-23.
- Sironi M, Claren R, Delpiano C, Santangelo M, Spinelli M. Cytological findings of adenocarcinomas metastatic to the breast. Diagn Cytopathol2001; 24:369-70.
- Domanski HA. Metastases to the breast from extramammary neoplasms: a report of six cases with diagnosis by fine needle aspiration cytology. Acta Cyto11996; 40:1293-300.
- Eisenberg AJ, Hadju SI, Wilhelmus J, Melamed MR, Kinne D. Preoperative aspiration cytology of breast tumours. Acta Cytol 1986; 30:135-46.
- D'Orsi CJ, Feldhaus L, Sonnenfeld M. Unusual lesions of the breast. Radio! Clin North Am1983; 21:67-80.
- Sniege N, Zachariah S, Fanning TV, Dekmezlan RH, Ordonez MG. Fine needle aspiration cytology of metastatic neoplasm in the breast. Am J Clin Pathol1989; 92:27-35.
- Hajdu SI, Urban JA. Cancers metastatic to the breast. Cancer 1972; 29:1691-6.
- McIntosh HI, Hooper AA, Millis RR, Greening WP. Metastatic carcinoma within the breast. Clin Onco11976; 2:393-401.
- Royen PM, Zitter FMH Jr. Ovarian carcinoma metastatic to the breast. Br J Radio! 1974; 47:356-7.
- Odile D, Gattuso P, Razan W, Moroz K, Durandhar N. Unusual cases of metastases to the breast. Acta Cytol 2002; 46:377-85.
- Hejmadi RK, Day I.J, Young JA. Extramammary metastatic neoplasm in the breast: a cytomorphological study of 11 cases. Cytopatho12003; 14:191-4.