Background: Acute upper gastrointestinal bleeding is a common medical emergency with an estimated incidence of 50-150 cases per one lakh annually and it has been noted as a major cause of hospital admission and deaths worldwide ranging from 0.9% to 26.5%.Hence, this study was aimed to know the clinical and endoscopic profile of patients presenting with acute upper GI bleed to our hospital and their possible etiologies.

Methods: This hospital based observational and cross-sectional study included sixty patients aged 18 years and above admitted in Department of General Medicine during the study period who presented with hematemesis or melena or both within 7 days.

Results: Among 60 patients, males were predominant (86.7%). Mean age of presentation was 41.93 ± 15.16 years. Most patients presented with both hematemesis and melena (51.7 %), 41.7 % patients had hematemesis only and 6.7 % patients had melena only. In our study, oesophageal varices were seen in 51.6 % patients, portal hypertensive gastropathy in 33.3 % patients, gastric ulcers in 11.7 % patients and duodenal ulcers in 5 % patients.

Conclusion: The majority of patients belonged to age group of 31-40 years with a male predilection and variceal bleed was the most common cause of Upper GI bleeding.

Keywords: Upper GI bleeding, oesophageal varices.

1. Jutabha R, Jensen DM, Friedman SL, McQuaid KR, Grendel JH. Acute Upper Gastrointestinal Bleeding, Current Diagnosis & Treatment in Gastroenterology. Mcgraw-Hill 2’’d edition inc.2003;53.
2. Thomopoulos KC, Vagenas KA, Vagianos CE, Margaritis VG, Blikas AP, Katsakoulis EC et al. Changes in aetiology and clinical outcome of acute upper gastrointestinal bleeding during the last 15 years. Eur J Gastroenterol Hepatol 2004;16:177-182.
3. Stanley AJ. Update on risk scoring systems for patients with upper gastrointestinal haemorrhage. World J Gastroenterol 2012; 18(22): 2739-2744.
4. Marshall JK, Collins SM, Gafni A. Prediction of resource utilization and case cost for acute nonvariceal upper gastrointestinal hemorrhage at a Canadian community hospital. Am J Gastroenterol. 1999; 94: 1841-6.
5. Jain J, Rawool A, Banait S, Maliye C. Clinical and endoscopic profile of patients with upper gastrointestinal bleeding in central rural India: A hospital based cross sectional study. JMGIMS 2018, Vol 23; Issue 1: 13-18.
6. Shah H, Manohar TP. Clinical and endoscopic parameters of upper gastrointestinal bleeding. International journal of community health and medical research. 2016; Vol 2; Issue 1:8-13.
7. Jaskolka JD, Binkhamis S, Prabhudesai V, Chawla TP. Acute gastrointestinal haemorrhage: Radiologic diagnosis and management. Can Assoc Radiol J 2013; 64:90-100.
8. Anand D, Gupta R, Dhar M, Ahuja V. Clinical and endoscopic profile of patients with upper gastrointestinal bleeding at tertiary care center of North India. J Dig Endosc 2014;5: 139-43.
9. Singh SP, Panigrahi MK. Spectrum of upper gastrointestinal haemorrhage in coastal Odisha. Trop Gastroenterol 2013; 34: 14-17.
10. Chaudhary S, Shakya S, Jaiswal N, Shahi A, Dhakal P, Chaudhary N. Clinical profile and outcome of patients presenting with acute upper gi bleeding in a tertiary care
11. Centre of western Nepal. Journal of Universal College of Medical Sciences.2018, 6(1):3-7
12. Rockey DC, Gastrointestinal bleeding- clinical presentation. Gastroenterol Clin of North America 34(2005) 581-582.
13. Shangavi Y, Rathod B J, Yagnik D Y. A clinical study on etiology, prognosis, outcome and role of endoscopy in upper gastrointestinal bleed in a tertiary care center. Internet Journal of Medical Update;2017 July; 12(2):4-9.
14. Sarwar S, Khan AA, Alam A. Non-Endoscopic Prediction of presence of Oesophageal varices in Cirrhosis. J Coll Physicians Surg. Pak 2005; 15(9): 528=31.
15. Rockall TA, Logan RF, Devlin HB, Northfield TC. Risk assessment after acute upper gastrointestinal hemorrhage. Gut. 1996;38: 316-21.

Dr Love Garg

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