Primary sclerosing cholangitis is an extra-intestinal manifestation of inflammatory bowel disease (IBD). About 5% of ulcerative colitis develops primary sclerosing cholangitis. Here we report a case presented with chronic loose stools and jaundice and was diagnosed to have Ulcerative colitis with associated Primary sclerosing cholangitis.

1. Kasper DL, Hauser SL, Jameson JL, Fauci AS, Longo DL, Loscalzo J. Harrison’s principle of internal medicine. 20th ed. New York: The McGraw-Hill Companies; 2018.p.2431-32.
2. Mertz A, Nguyen NA, Katsanos KH, Kwok RM. Primary sclerosing cholangitis and inflammatory bowel disease comorbidity: an update of the evidence. Annals of gastroenterology. 2019 Mar;32(2):124.
3. Goode EC, Rushbrook SM. A review of the medical treatment of primary sclerosing cholangitis in the 21^st Therapeutics advances in chronic disease. 2016 Jan;7(1):68-85.

Uthaya Sankar M.K
Professor, Department of General  Medicine, Sri  Manakula Vinayagar  Medical College and Hospital, Puducherry-605107, India