Title: Infantile Hypertrophic Pyloric Stenosis, A Mendelian Inheritance or Multifactorial Influence: A Case Report

Authors: Dr Vipan Garg, Dr Amar Thakur, Dr Mohit Bajaj, Dr Swati Mahajan, Dr Anju Bala, Dr Amit Kumar

 DOI: https://dx.doi.org/10.18535/jmscr/v7i12.25

Abstract

Background: Infantile hypertrophic pyloric stenosis (IHPS) is one of the surgical causes of “protracted vomiting in early infancy”. This condition is characterized by abnormal thickening of the muscular wall of the pylorus, hence it is the commonest cause of gastric outlet obstruction in infant. Males (especially first-borns) are affected approximately 4 to 6 times as often as females. The offspring of a mother and, to a lesser extent, the father who had pyloric stenosisare at higher risk for pyloric stenosis and it develops in approximately 20% of the male and 10% of the female descendants of a mother who had pyloric stenosis. The incidence of pyloric stenosis has been found more in B and O blood groups. Pyloric stenosis is usually presents at 3-4 weeks of life and is more concordant in monozygotic.

Keywords: Pyloric stenosis, newborn.

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