Title: Epidemiology of lung cancer patients admitted to tertiary level hospitals in Karnataka
Authors: Dr SL Chandargi, MD, Dr GS Mahishale, MD, Dr Deepa Allolli, MD, Dr Ashok Yankanchi, MD, Dr Sachin Shetagar, MD
DOI: https://dx.doi.org/10.18535/jmscr/v7i11.159
Abstract
Introduction: Epidemiological observations confirm the significant burden of lung cancer in India, contributing significantly toward the cancer morbidity and mortality. The present study was conducted to assess the epidemiology as well the clinical and radiological features of various types of lung cancer and the recent trends in the demographic patterns of patients with lung cancer.
Methodology: This retrospective study was done on patients with a histological diagnosis of carcinoma lung. Using a pre-designed semi-structured study proforma, patient information like demography, smoking history, radiological findings and histopathological diagnosis was noted.
Results: Mean age of the patients included in the study was 55 years, males comprised 65% of the study population and half of all study participants were smokers. Most common symptoms among the patients were cough, dyspnea and loss of appetite. Histologically, adenocarcinoma was the most common type of cancer (38%), followed by squamous cell carcinoma (25%). Large cell and small cell carcinoma was 8% and 9% respectively. Undifferentiated cases comprised 20% of the population. Squamous cell cancer cases and small cell cancer cases were aged on the higher side, adenocarcinoma and undifferentiated cancer cases were aged on the lower side. Gender, smoking status and radiological appearance were not significantly different between the various cancer types.
Conclusions: In our study population, adenocarcinoma was the most common type of lung cancer histologically. Squamous cell and small cell cancer cases were aged on the higher side, while adenocarcinoma and undifferentiated cancer cases were aged on the lower side.
Keywords: Lung cancer; Epidemiology; Histology; Smoking status.
References
- Bray F, Ferlay J, Soerjomataram I, Siegel RL, Torre LA, Jemal A. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA: a cancer journal for clinicians. 2018 Nov;68(6): 394-424.
- Viswanathan R, Sen Gupta, Iyer PV. Incidence of primary lung cancer in India. Thorax1962;17:73‐6.
- Zhong L, Goldberg MS, Parent ME, Hanley JA. Exposure to environmental tobacco smoke and the risk of lung cancer: A meta‐analysis. Lung Cancer 2000; 27:3‐18.
- Chute CG, Greenberg ER, Baron J, et al. Presenting conditions of 1539 population-based lung cancer patients by cell type and stage in New Hampshire and Vermont. Cancer 1985; 56:2107.
- Hirshberg B, Biran I, Glazer M, Kramer MR. Hemoptysis: etiology, evaluation, and outcome in a tertiary referral hospital. Chest 1997; 112:440.
- Colice GL. Detecting lung cancer as a cause of hemoptysis in patients with a normal chest radiograph: bronchoscopy vs CT. Chest 1997; 111:877.
- Krishnamurthy A, Vijayalakshmi R, Gadigi V, Ranganathan R, Sagar TG. The relevance of “nonsmoking‐associated lung cancer” in India: A single‐centre experience. Indian J Cancer 2012;49:82‐8.
- Malik PS, Sharma MC, Mohanti BK, Shukla NK, Deo S, Mohan A, et al.Clinico‐pathological pro le of lung cancer at AIIMS: A changing paradigmin India.Asian Pac J Cancer Prev 2013;14:489‐94.