Title: Status of Bone mineral density in adult North Indian population using Dual-energy x-ray absorptiometry (DEXA) Scan
Authors: Dr Anisha Aggarwal, Dr Anshu Mittal, Dr Harsimranjit Kaur Natt, Dr Pradeep Aggarwal, Dr Amnajot Kaur Chauhan, Dr Suryakant
DOI: https://dx.doi.org/10.18535/jmscr/v7i10.41
Abstract
Introduction: Osteoporosis and osteopenia are a major public health problem, associated with substantial morbidity and socio-economic burden. An early detection can help in reducing the fracture rates and overall socio-economic burden. The present study was conducted to find out its burden in the society and give appropriate care to the participants.
Material & Methods: A cross sectional study conducted in rural field practice area of MMIMSR between October, 2018 to March, 2019. BMD at postero-anterior lumbar spine (L2–L4) and bilateral hip joint was assessed by Hologic Explorer QDR Series bone densitometer for each participant.
Results: In the current study, he overall prevalence of osteoporosis was found to be higher among the male participants (26.25%) than their female counterparts (16.25%). Maximum participants who were osteoporotic were between the age group 51 to 70 years (17.5%) followed by 71 to ≥80 year’s old patients (11.25%).
Conclusion: A significantly larger proportion of otherwise normal healthy men in our community had osteoporosis as compared to the previous notions known. It is therefore necessary to create awareness among men and women from Indian subcontinent, irrespective of their geographic location, about the risk of osteoporosis and educate those regarding preventive measures to avoid future fractures secondary to osteoporosis. There is also a need for large community-based studies so that high-risk population can be picked up and early interventions like adequate calcium intake, vitamin D supplementation, and other life style changes can be instituted.
Keywords: Osteoporosis, Osteopenia, DEXA-Scan, Bone density.
References
- Das BG, Deb A , Chattopadhyay A, Basu M, Bhattacharya J. Prevalence and risk factors of osteopenia and osteoporosis in Indian women. IOSR-JDMS, 2016 Feb;15(2):15-18.
- Khadilkar AV, Mandilk RM. Epidemiology and treatment of osteoporosis in women: an Indian perspective. Dovepress, 2015, Oct;2015:841-850.
- Kanis JA, Delmas P, Burckhardt P, Cooper C, Torgerson D. Guidelines for diagnosis and management of osteoporosis. The European Foundation for Osteoporosis and Bone Disease. Osteoporos Int. 1997;7(4):390–406
- Mithal A, Kaur P. Osteoporosis in Asia: a call to action. CurrOsteoporos Rep. 2012;10(4):245–247.
- Afzelius P, Garding MM, Molsted S. Dual-energy X-ray Absorptiometry of both hips . Helps appropriate diagnosis of low bone mineral density and osteoporosis. Diagnosis 2017, Jul;7(14):44-50.
- Lewiecki EM, Kendler DL, Kiebzak GM, Schmeer P, Prince RL,El-Hajj Fuleihan G, et al. Special report on the official positions of the International Society for Clinical Densitometry. Osteoporos Int 2004;15(10):779-84.
- Anburajan M, Kumar DA, Sapthagirivasan V. Evaluation of osteoporosis in Indian women and men using peripheral Dual-Energy X-ray Absorpitometry (Pdxa). International conference on Bioscience, Biochemistry and Bioinformatics. 2011;5:470-474.
- Kanis JA. Assessment of fracture risk and its application to screening for postmenopausal osteoporosis: synopsis of a WHO report. WHO Study Group. Osteoporos Int 1994;4:368-81.
- Babu AS, Ikbal FM, Noone MS, Joseph AN, Samuel P. Osteoporosis and osteopenia in India: A few more observations. Indian J Med Sci 2009;63:76-7.
- Melton LJ, Atkinson EJ, O’Conner MK, O’Fallon WM, Riggs BL. Bone density and fracture risk in men. Journal of Bone and Mineral research 1998;13(12):1915-1923.
- Shetty S, Kapoor N, Naik D, Asha HS, Prabu S, Thomas N et al. Osteoporosis in healthy south Indian males and the influence of lifestyle factors and vitamin D status on bone mineral density. Journal of osteoporosis 2014, Nov;2014:20-25.
- Acharya S, Srivastava A, Sen I. Osteoporosis in Indian women aged 40-60 years. Arch Osteoporos.2010;20:1121-1126.
- Agrawal T, Verma AK. Cross sectional study of osteoporosis among women. Medical Journal Armed Forces India. 2012, Nov;69:168-171.
- Choe HS, Lee JH, Min DK, Shin SH. Comparison of vertebral and femoral bone mineral debsity in adult females. J Phys Ther Sci.2016;28:1928-1931.
- Dutta N, Saika AM, Saika AM, Das AK. Status of bone mineral density in adult population using calcaneal ultrasound bone densitometer : A study from Assam, India. Indian journal of basic and applied medical research. 2015, Jun;4(3):150-158.
- Looker AC, Borrud AG, Hughes DH, Shepherd JA, Wright NC. Osteoporosis or low bone mass at the femur neck or lumbar spine in Older adults: United States, 2005-2008. NCHS Data Brief. 2012;Apr;93:1-8.
- Paul TV, Thomas N, Seshadri MS, Oommen R, Jose A, Mahendri NV. Prevalence of osteoporosis in ambulatory pstmenopausal women from a semiurban region in Southern India: relationship in calcium nutrition and Vitamin D status. Endocr Pract. 2008, Sep;14(6):665-671.
- Lee J, Lee S, Jang S, Ryu OH. Age-related changes in the prevalence of osteoporosis according to gender and skeletal site : The Korea National health and nutrition examination survey 2008-2010. Endocrinol Metab. 2013, May;28:180-191.
- Thangwijtra S, Sakondhavat C, Soontrapa S, Kaewrudee S, Somboonporn W. Prevalence of osteoporosis in postmenopausal women at Sriagrind Hospital , KhonKaen University. The Journal of obstretics and gynaecology. 2010, Jan; 18:26-34.
- Hilmi I, Sunderesvaran K, Ananda V, Sarji SA, Arumugam K, Goh KL. Increased fracture risk and osteoporosis not associated with vitamin D levels in Malaysian patients with inflammatory bowel disease. The journal of clinical endocrinology & metabolism. 2013,Jun;98 (6): 2415-2421.