Title: Non keratinizing squamous cell carcinoma of nasal cavity-A rare case of confusing nomenclature
Authors: Kishore Vatsala, M.D., Singh Neeraj Kumar, M.D., Kotasthane Dhananjay S, M.D.
DOI: https://dx.doi.org/10.18535/jmscr/v7i10.28
Abstract
Malignant sinonasal carcinomas constitute <1% of all cancers with annual incidence of 3.5 per ten thousand population and of these, 15-20% are non-keratinizing with a male preponderance. We report a case of 56 year male with history of nasal obstruction and discharge. CECT showed large, expansile mass predominantly in left nasal cavity with destruction of adjacent sinuses. A biopsy was taken which revealed Non-keratinizing carcinoma (transitional type).Rarity of this case and multiple confusing nomenclatures prompted us to report this case.
Keywords: Non keratinizing carcinoma, transitional cell cancer, sinonasal cancer.
References
- Jhawar Kavish, Jain A. K., Nigam Ritu, Sachan Manish Kumar, Freni J. K. Transitional Cell Carcinoma of Nasal Cavity: A Rare Case Report. Journal of Evolution of Medical and Dental Sciences 2014;3(30): 8399-8402
- Gupta Kanupriya, Gupta Jatin. Non keratinizing squamous cell carcinoma – a diagnosis of confusing nomenclature. European journal of pharmaceutical and medical research2017;4(6):717-718
- Osborn DA. Nature and behaviour of transitional tumors of the upper respiratory tract. Cancer 1970;25(1):50-60.
- Osborn DA. Transitional cell growths of the upper respiratory tract. J Laryngol Otol 1956; 70: 574–587.
- Pilch BZ, Bouquot J, Thompson LDR. Squamous cell carcinoma. In: Barnes L, Eveson JW, Reichart P, Sidransky D, editors. World Health Organization classification of tumors. Pathology and genetics of head and neck tumors. Lyon: IARC Press; 2005:15-7.
- Zarbo RJ, Torres FX, Gomez J. Nasal cavity and paranasal sinuses: embryology, anatomy, histology and pathology. In: Pilch BZ, editor. Head and Neck Surgical Pathology. Philadelphia: Lippincott Williams & Wilkins ; 2000:80-156.
- Rashid Nur Hashima Abdul, Pauzi Hayati Suria Md, Tan GoekChin ,Husain Salina, Yunus Mohd Razi Mohammad, Gendeh Balwant S. Non keratinizing Carcinoma of the Sinonasal Tract: A Diagnosis of Confusing Nomenclature. Philipp J Otolaryngol Head Neck Surg 2011; 26 (2):21-24
- James S. Lewis Jr. Sinonasal Squamous Cell Carcinoma: A Review with Emphasis on Emerging Histologic Subtypes and the Role of Human Head and Neck Pathol 2016;10:60–67.