Acute stroke is one of the common causes of morbidity and mortality in India. In the Study, we are trying to estimate the prevalence of undiagnosed thyroid disorder/dysfunction in acute ischemic stroke patients and to correlate the relationship between thyroid dysfunction and acute ischemic stroke.

1. Akram Mohammed Al-Mahdawi; Thyroid function test in patient with ischemic stroke; karbala J. Med. Vol.6, No.2, Dec, 2013
2. Davidson s principles and practice of Medicine 23rd edition
3. Ganong s review of Medical Physiology 25th edition
4. Harrison s principles of Medicine 19th edition
5. Thyroid Dysfunction in Acute ischemic stroke in Medical Intensive care unit in Zagazig university hospitals; International Journal of Advanced Research(2014), Volume 2, Issue 7, 385-391
6. Williams textbook of Endocrinology 13th edition
7. Deb P, Sharma S and Hassan KM (2010). Pathophysiologic mechanisms of acute ischemic stroke. An overview with emphasis on therapeutic significance beyond thrombolysis. Pathophysiology. 17 (3): 197–218.
8. Fisher M, and Mcleod M (2008): Stroke. Lancet; 371: 1612-1623.
9. Feigin VL, Weibers DO, Nikitin YP, et al (1998): Risk factors of ischemic stroke in a Russian Community, a populationbased casecontrol study. Stroke. 29: 34-39
10. Surks MI, Onrz E, DeNms GH et al.,(2004): Subclinical thyroid disease: scientific review and guidelines for diagnosis and management. J AMA, 291 :228-38.
11. Fazio S, Palmieri EA, Lombardi G et al (2004): Effects of Thyroid Hormone on the Cardiovascular System. Recent Progr Horm Res, 59:31-50.
12. Osman F, Daykin J, Sheppard M, et al (2000):, Cardiac rhythm abnormalities in thyrotoxicosis - the explanation for excess vascular mortality. J Endocrinol;164:321-329.
13. Bengtsson D, Brudin L, Wanby P and Carlsson M (2012): Previously unknown thyroid dysfunction in patients with acute iscehmic stroke. Acta Neurol Scand: 136: 98-102.
14. Hage M, Zantout SM, and Azar ST (2011):, Thyroid Disorders and Diabetes Mellitus, Journal of Thyroid Research.,77:312-320.
15. Warlow C, Sudlow C, Dennis M, Wardlaw J, Sandercock P.Stroke. Lancet 2003; 362:1211– 1224.
16. Allan H. Ropper, Martin A.Samuels. Cerebrovascular Diseases, Adams and Victor’s Priciples of Neurology, Ninth Edition; 2009:
17. Donnan GA, Fisher M, Macleod M, Davis SM. Stroke. Lancet 2008;371: 1612–1623.
18. Coceani M, Iervasi G, Pingitore A, et al. Thyroid hormone and coronary artery disease: from clinical correlations to prognostic implications. Clin Cardiol. Jul 2009;32(7):380-5
19. Paul S. Jellinger, Donald A. Smith, Adi E. Mehta. AACE lipid and Atherosclerosis Guidelines. Endocr Pract 2012; 18(Suppl 1)
20. Wade SS, Claiborne J, Donald E. Cerebrovascular Diseases. In: Stephen LH (edr). Harrison's Neurology in Clinical Medicine. 1^st New York: McGraw Hill; 2006: 233-260.
21. Weetman, AP, McGregor, AM. Autoimmune thyroid disease further developments in our understanding. Endocr Rev 1994; 15:788.
22. Towfighi, A, Saver, JL, Engelhardt, R, Ovbiagele, B. A midlife stroke surge among women in the United States. Neurology 2007; 69:1898.
23. Lewington S, Clarke R, Qizilbash N, Peto R, Collins R. Age-specific relevance of usual blood pressure to vascular mortality: a metaanalysis of individual data for one million adults in 61 prospective studies. Lancet 2002; 360:1903–1913.

Dr A. Thenmozhi M.D