Title: Bilateral Nephrolithiasis caused by Primary Hyperparathyroidism: A Case Report
Authors: Sari Rahmawati, Rahmat Cahyanur
DOI: https://dx.doi.org/10.18535/jmscr/v7i9.74
Abstract
Nephrolithiasis is one of the most common urologic condition, which is now likely to increase in time and become a burden on the health care system. Primary hyperparathyroidism (PHPT) is a disorder of calcium, phosphate, and bone metabolism due to the increase of parathyroid hormone (PTH). The incidence of PHPT is about three times higher in females than in males, approximately 66 cases per 100,000 person-years in females. This case report describes a 62-year-old woman presented with bilateral nephrolithiasis with urinary tract infection. We investigate further the cause of bilateral nephrolithiasis and hypercalcemia was detected, which then led us to diagnosed primary hyperparathyroidism as the cause.
Keywords: Bilateral nephrolithiasis, primary hyperparathyroidism.
References
- Potts JT, Jüppner H. Disorders of the parathyroid gland and calcium homeostasis. In: Kasper DL, Hauser SL, Jameson JL, Fauci AS, Longo DL, Loscalzo J, editors. Harrison's principles of internal medicine. 19th ed. New York: McGraw-Hill; 2015. p. 2466-88.
- Insogna KL. Primary hyperparathyroidism. N Engl J Med. 2018 Sep 13;379(11):1050-9.
- Yeh MW, Ituarte PH, Zhou HC, Nishimoto S, Liu IL, Harari A, et al. Incidence and prevalence of primary hyperparathyroidism in a racially mixed population. J Clin Endocrinol Metab. 2013 Mar;98(3):1122-9.
- Ejlsmark-Svensson H, Bislev LS, Rolighed L, Sikjaer T, Rejnmark L. Predictors of renal function and calcifications in primary hyperparathyroidism: A nested case-control study. J Clin Endocrinol Metab. 2018 Sep 1;103(9):3574-83.
- Lila AR, Sarathi V, Jagtap V, Bandgar T, Menon PS, Shah NS. Renal manifestations of primary hyperparathyroidism. Indian J Endocrinol Metab. 2012 Mar;16(2):258-62.
- Silva BC, Cusano NE, Bilezikian JP. Primary hyperparathyroidism. Best Pract Res Clin Endocrinol Metab. 2018 Sep 28:101247.
- Alelign T, Petros B. Kidney stone disease: An update on current concepts. Adv Urol. 2018;2018:3068365.
- Curhan GC, Aronson SD, Preminger GM. Diagnosis and acute management of suspected nephrolithiasis in adults: UpToDate; [updated 2-7-2019]. Available from: https://www.uptodate.com/contents/diagnosis-and-acute-management-of-suspected-nephrolithiasis-in-adults.
- Gambaro G, Croppi E, Coe F, Lingeman J, Moe O, Worcester E, et al. Metabolic diagnosis and medical prevention of calcium nephrolithiasis and its systemic manifestations: A consensus statement. J Nephrol. 2016 Dec;29(6):715-34.
- Pfau A, Knauf F. Update on nephrolithiasis: Core curriculum 2016. Am J Kidney Dis. 2016 Dec;68(6):973-85.
- Walker MD, Silverberg SJ. Primary hyperparathyroidism. Nat Rev Endocrinol. 2018 Feb;14(2):115-25.
- Rejnmark L, Vestergaard P, Mosekilde L. Nephrolithiasis and renal calcifications in primary hyperparathyroidism. J Clin Endocrinol Metab. 2011 Aug;96(8):2377-85.
- Bilezikian JP. Primary hyperparathyro-idism. J Clin Endocrinol Metab. 2018 Nov 1;103(11):3993-4004.
- Yorke E, Atiase Y, J A. Primary hyperparathyroidism: An update and in-depth review of the literature. International Journal of Endocrinology and Metabolic Disorders. 2018 01/01;4.
- Wilhelm SM, Wang TS, Ruan DT, Lee JA, Asa SL, Duh QY, et al. The american association of endocrine surgeons guidelines for definitive management of primary hyperparathyroidism. JAMA Surg. 2016 Oct 1;151(10):959-68.