Title: Maternal Outcome in Pregnancies with Thrombocytopenia

Authors: Dr Rinku G, Dr. M I Geetha

 DOI: https://dx.doi.org/10.18535/jmscr/v7i9.18

Abstract

     

Background: Thrombocytopenia is a common occurrence in pregnancy. Although pregnancy is associated with physiological changes in platelet count, several pathological conditions cause thrombocytopenia, which can have a significant impact on the mother and the baby. The present study aims at the maternal outcome of pregnancies in patients with thrombocytopenia during pregnancy.

Materials and Methods: Comparative cross sectional survey conducted in SAT Hospital for a period of one year.

Results: In our study gestational thrombocytopenia constitutes 40% of cases and majority are mild type.  Moderate and severe types were constituted by Pre eclampsia 10.8%, HELLP syndrome 17.4%, ITP 11.4 % SLE 9% and DIC especially following grade III abruption. Out of moderate to severe cases 13.8% developed post-partum hemorrhage requiring blood and blood products transfusion.  Maternal mortality (1 case) occurred in SLE group due to intractable pulmonary edema. Cesarean section rate was more in thrombocytopenia group.

Conclusion: Gestational Thrombocytopenia group had a favorable outcome in our study.  The other group constituted by pre eclampsia SLE, ITP, DIC had complications like PPH, abruptions, DIC requiring multi-disciplinary approach.

Keywords: Thrombocytopenia, ITP (immune thrombocytopenic purpura), SLE (systemic lupus erythamatosis).

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