Background: The sellar and parasellar region is an anatomically complex area that represents a critical junction for important contiguous structures. A number of pathological processes occur in the sellar/para/ suprasellar region including: neoplastic, inflammatory, infectious, developmental and vascular abnormalities and the presentation of the various lesions can mimic the pituitary adenonmas clinically, endocrinologically and in the radiological presentation.

The overwhelming majority of sellar region masses are pituitary adenomas (85%), followed by craniopharyngiomas (3%), Rathke cleft cysts (2%), meningiomas (1%), and metastases (0.5%); all other lesions, such as hypophysitis, pituicytoma, spindle cell oncocytoma, and granular cell tumor of neurohypophysis, are rare lesions. The purpose here is to study the histopathological spectrum of sellar, suprasellar and parasellar lesion in biopsy specimen received in Department of Pathology of SMS Medical College and Hospital, Jaipur.

Objective: To find out proportion of various morphological types of sellar, suprasellar and parasellar lesions in intracranial lesions.

Material and Methods: A total of 671 samples of intracranial SOL biopsy specimens were received from IPD, out of which 100 samples of sellar / suprasellar biopsies were enrolled for present study. Histopathological analysis was done.

Results: Out of 100 cases Pituitary Adenoma was the commonest lesion followed by Craniopharyngioma. The number of male and female patients was approximately same, ratio was 1.27:1. Among females, most common age group was 41 to 50 years and in males it was 31 to 40 years.

Conclusion: Pituitary adenomas being the most frequent lesion encountered in the sellar/ parasellar/suprasellar area in our institute, followed by non-adenomatous lesions including meningiomas and the potentially malignant parasellar lesion Craniopharyngiomas.

Keywords: Sellar-Suprasellar lesions, Parasellar lesion, Pituitary tumor.

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Om Prakash

Department of Pathology, Sawai Man Singh Medical College and Hospital, Jaipur, Rajasthan