Introduction: Dengue infection is increasing proportionally to increased urbanization and compromised sanitation measures. Dengue infection poses a huge burden to the health-care system. Dengue infection vary in severity, ranging from influenza-like self-limiting illness to life-threatening dengue hemorrhagic fever (DHF) and dengue shock syndrome (DSS) which, if left untreated, are associated with mortality as high as 20%. Early diagnosis and management can decrease case fatality rate significantly.

Objective: To assess the clinical profile of dengue infection and to evaluate the outcome of dengue fever.

Material and Method: In this prospective observational study 129 patients who visited to Rohilkhand Medical College And Hospital between 1^st Jan 2018 to 31^st Dec 2018 were included. Those patients with confirmed dengue, with NS1 antigen and/or IgM dengue antibody positive were included in this study. Detailed history was taken and clinical examination was performed and laboratory investigations were done.

Results: 129 patients were studied, majority were males. Fever was present in 100% of patients followed by headache, myalgia. In 90 cases platelet count was less than 50,000/cumm of which bleeding manifestation was found in 9 patients. Plerual effusion and ascitis were observed in 26 and 21 cases respectively. Hepatomegaly was noted in 19 cases and splenomegaly in 17. Leucopenia was present in 26 cases whereas raised liver enzymes were present in 114cases. The mortality rate was 1.55 %.

Conclusion: Dengue epidemic has increased in recent past probably due to unplanned urbanization with rapid construction activities, unhygienic condition and poor sanitation facilities contributing fertile breeding soil for mosquitoes. Early diagnosis and management can decrease mortality and morbidity of illness. Platelet transfusions have little role in management of dengue patients.

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Kamlesh Taori

Junior Resident, MD Medicine, Rohilkhand Medical College, Bareilly, India