Extrapyramidal side effects (EPS), commonly referred to as Drug-Induced Movement Disorders (DIMD), are among the most common adverse drug effects from dopamine-receptor blocking agents. The EPS reported with TCA include dyskinesia, akathisia, Rabbit syndrome and dystonia. This case report describes a case of acute dyskinesia and akathisia following ingestion of Amitriptyline in a female taking Oral contraceptive Pills (OCP). Clinicians should be aware of this possible interaction before prescribing dopamine blocking agents to women on OCPs. Careful monitoring and appropriate patient education is necessary.

Keyword: Extrapyramidal side effects, Drug-Induced Movement Disorders, Amitriptyline, Tricyclic Antidepressants, Oral Contraceptive Pills.

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Dr Vijayavarman V

PG Junior Resident, Dept of Medicine, U.P. University of Medical Sciences, Saifai, Etawah (Uttar Pradesh)