Title: Efficacy of Psidium guajava leaf extract on Streptococcus mutans and Enterococcus faecalis – an in vitro study

Authors: Dr Vidya Venugopal, Dr Gopinath Prakasan, Sandeep P M, Dr Anuradha E Sunil, Dr Archana Mukunda, Dr Steffy Rachel Samuel

 DOI: https://dx.doi.org/10.18535/jmscr/v7i5.121

Abstract

Introduction: The general health of the body is governed largely by oral health. The most common oral diseases are dental caries and gingivitis both of which are caused by micro organisms. Streptococcus mutans and Enterococcus faecalis are the common causative bacteria which are traditionally treated with antibiotics. Many herbal preparations have also known to exhibit potent antibacterial activity.

Objective: To evaluate the antibacterial activity of Psidium guvajava leaf extract on Streptococcus mutans and Enterococcus faecalis

Methods: In vitro study, in which the ethanolic extract of Psidium guajava leaf extract was prepared using solvent extraction apparatus. The extract was then diluted in normal saline to 3 different concentrations. Well diffusion method was used to determine the zone of inhibition of various concentrations of Psidium guajava leaf extract against Streptococcus mutans and Enterococcus faecalis. Zone of inhibition was measured in mm.

Result: At all concentrations guava leaf extract showed zone of inhibition against Streptococcus mutans (S. mutan) and Enterococcus faecalis (E.faecalis). Zone of inhibition increased with concentration of the extract.

Conclusion: Psidium guajava leaf extract demonstrate an anti-microbial property against Streptococcus mutans and Enterococcus faecalis

Keywords: Enterococcus faecalis, Psidium guajava, Streptococcus mutans, zone of inhibition  .

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