Title: Comparing the Efficacy of Visual Inspection with Acetic Acid and Pap Smear as a Screening tool for Cervical Pre invasive Lesion
Authors: Dr Veena Kumari Sinha, Dr Puja Sinha, Dr Abha Rani Sinha
DOI: https://dx.doi.org/10.18535/jmscr/v7i3.83
Abstract
Objective: To compare the efficacy of pap smear with VIA (Visual Inspection of Cervix after application of Acetic acid) as screening of CIN and early cancer cervix.
Material & Methods: 350 patient who had relevant history and clinical suspicion were subjected to pap smear, VIA and biopsy. The sensitivity and specificity, false positive rate and false negative rate were calculated for VIA and Pap smear.
Results: This study showed sensitivity and specificity of pap smear 81% and 97.8 % respectively and that of VIA were 86.1% and 99.1% respectively.
Conclusion: VIA is a suitable primary screening procedure in developing countries like India as it is inexpensive, simple and treatment can be administered at the same time.
References
- WHO (1986) control of cancer of cervix Uteri A WHO meeting Bulletin of WHO 1986 64. 607-18.
- National cancer Registry programmers consolidated respect of the population based cancer. Registries 2001 – 2004. 71 – 2.
- GLOBOCON 2002, Cancer incidence mortality and prevalence in India.
- Maria ES, Lynne G, Paul DB. Cervical cancer screening in devpping countries. Prim Care updates ob/Gyn. 200; 7:118.2
- Sankarnarayanan R, Wesley R. Somnath T. Dhakad N, Chandralekha B. Sebasthan P et al;. Test charactestics of visual inspection with 4% acetic acid and Lugols iodine in cervical cancer screening in Kerala, India. International Journal of cancer: 2003 Vol 106 page No. 404 – 408.
- Kumar, Vinay: Abbas, Abdul K; Fausto, Nelson & Mitchell, Richard N. (2007). Robbins Basic Pathology (8the ed). Saunder Elsevier DP 718 – 721 ISBN978 – 1 4160 – 2973 – 1.
- Agorastos T. Miliaras D, L ambropoulos A. Chrisafi S. Kotsis A, Manthos A, Bontis J (2005). Detection and typing of human pappilomavirus DNA in uterine cervices with coexistent grade 1 and grade 3 inpraepitheliae neoplasia; biologic progression or independent lesions? Eur J Obstet Gynecol Reprod Biol 121 (1): 99 – 103.
- Goel A, Gandhi G. Visual Inspection of cervix with acetic acid for cervical Intraepithelial lesion Int J Gynecol Obsted 2005; 88:25-30.