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Category: Volume 07 Issue 02 February 2019
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Title: Study of pediatric uropathogens and their antimicrobial susceptibility pattern in a tertiary care hospital of eastern India

Authors: Dr Priyanka Saha, Dr Soma Mondal

 DOI: https://dx.doi.org/10.18535/jmscr/v7i2.185

Abstract

Urinary Tract Infection (UTI) is one of the most common childhood bacterial infection. Early diagnosis, adequate therapy and prolonged follow-up are utmost important to reduce morbidity and long-term complications like renal scarring, hypertension, and chronic renal failure.

Objective: The study was carried out to find out the prevalent uropathogens causing pediatric UTI and their antibiotic susceptibility pattern.

Method: A total 728 urine specimens from children aged 0-12 years were processed in a tertiary care hospital from November 2015 to June 2016 . All bacterial isolates were identified by biochemical test and antimicrobial susceptibility testing was done by Kirby-Bauer disc diffusion test. Result:  Prevalence of urinary tract infection was found to be 15.52% among the study population. Overall it was more common in female child. E. coli was the commonest bacteria (45.13%) isolated, followed by Enterococcus spp (31.85%), Klebsiella pneumonia (8.84%), Staphylococcus aureus (3.5%), Candida spp (3.5%), Staphylococcus saprophyticus  (2.6%), Proteus vulgaris (1.76%), Pseudomonas spp (1.76 %), Morganella morganii (0.8%). Most of the oral antibiotics like cotrimoxazole, amoxyclav, ciprofloxacin, cefixime were highly resistant to urinary isolates. Nitrofurantoin was found to be the most sensitive (>65%) drug. Gram negative bacteria also showed high sensitivity to meropenem (71.22%) whereas linezolid (100%) and vancomycin were most sensitive drug for gram positive cocci (>90%)).

Conclusion: Antibiotic resistance has now become a big problem therefore it is an important issue need to be urgently addressed by the policy makers to formulate a strict antibiotics prescription policy in our country.

Keywords:  Paediatric, UTI,  Antibiotic sensitivity.

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Corresponding Author

Dr Soma Mondal

Associate Professor, College of Medicine and JNM hospital, W.B.U.H.S, Kalyani, Nadia

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