Title: Serum Amylase Levels in Acute Organophosphorus Poisoning and It’s Correlation with Clinical Severity

Authors: Dr Kamleshwar Mahto, Dr Rajesh Manocha, Dr Charanjeet Kaur

 DOI: https://dx.doi.org/10.18535/jmscr/v7i2.118

Abstract

Introduction

Organophosphorus (OP) compounds have been widely used for a few decades in agriculture for crop protection and pest control. India is a predominantly agrarian country with about 60-80% rural population. Pesticides are routinely used for advanced farming. Therefore, a pesticide is an easy access source for suicidal purpose particularly after trivial family squabbles. Poisoning is seldom included as a priority for health research in India, though every year, hundreds of people are losing their lives prematurely from pesticide poisoning. Vomiting soon after consumption of pesticide and with its smell easily detected even by a lay person poses no diagnostic difficulty. Thereby, quite often, the victim is brought to a health center within an hour of consumption of the pesticide – usually Organo-Phosphorus Compounds (OHPs). This is the “Golden Hour” for clinical intervention, before irreversible “ageing” of toxic compounds in blood occurs. Primary Health Centers in India are known for lack of drugs, doctors and application of evidence-based treatment.

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