Title: A Comparative Study of 0.1% Bupivacaine V/S 0.18% Ropivacaine in Labour Analgesia

Authors: Dr Voviliveni Srikala, Dr Botla Chandrasekhar

 DOI: https://dx.doi.org/10.18535/jmscr/v7i2.75

Abstract

This study was done to compare the effects of 0.1% Bupivacaine v/s 0.18% Ropivacaine with by lumbar epidural technique in producing labour analgesia. Hundred primigravida parturients in the age group of 18-26 years belonging to ASA grade 1 and 2, all being primigravidae were randomly selected and divided into 2 groups of 50 each. Group 1 parturients were given 0.1% Bupivacaine, Group -2 parturients were given 0.18% Ropivacaine by lumbar epidural technique. Haemodynamic monitoring of the mother and fetus were done during the procedure. Onset of analgesia 8.18±1.6&10.68±6.95, duration of analgesia 100.68±9.19 & 122.19±14.24, quality of analgesia1.42±1.9&1.34±1.5 and duration of labor 302.9±42.68 & 290.18±47.49 in Bupivacaine and ropivaine groups respectively. Duration of analgesia and total no of doses required were significant. Incidence of instrumental deliveries, incidence of side effects and neonatal outcome were recorded, compared and analyzed statistically. The duration of analgesia with the 1st dose was significantly more in the group-2 also the requirement of top up doses was also less in group -2 and the quality of analgesia is equal in both group-1&group-2. There was no significant increase in the requirement of instrumentation, surgical intervention in both the groups. Neonatal outcome was good and almost equal in both the groups without any respiratory depression.

Keywords: Labour, Epidural analgesia, Bupivacaine, Ropivacaine, VAS score.

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