Title: A study of FNAC for evaluation of cervical lymphadenopathy in tertiary care hospital of Jharkhand, Dhanbad
Authors: Dr Jyoti Ranjan Prasad, Dr Raj Kumar Prasad, Dr Leena Singh, Dr Leena Singh
DOI: https://dx.doi.org/10.18535/jmscr/v7i2.42
Abstract
Introduction: FNAC is a simple, rapid and minimally invasive technique employed for evaluation of a wide variety of superficial palpable lesions. Enlarged cervical lymph nodes are a common presenting complain across patients of all age groups which are subjected to FNAC. This is a standard baseline study for knowing the pattern of cervical lymphadenopathy. Ina study conducted by Gaurav Batni et al, almost half of the lymph nodes (51.56 %) were reactive without a known cause which was followed by tubercular (28.12 %), malignancy (17.18 %) and lymphoma (3. 1%).Higher incidence of malignancy was seen in 51 -60 years and more than 60 years age group. Tuberculous lymphadenitis was common in 21 – 30 years age group. O A Silas et al observed-on total of 56 samples, out of which 76.8 % were inflammatory and 23.2 % malignant. However tuberculous lesions were seen in only 9.3 % cases.
Material and Methods: A retrospective study will be conducted by analyzing the reports of cervical lymph nodes FNAC from June 2015 to November 2017 at pathology department of Patliputra Medical College, Dhanbad in its cytology section. The study would be done on FNAC with 21/22-gauge needle with 20 ml plastic disposable syringe. Three smears would be prepared –
- Air dried smear stained with MGG stain
- Wet fixed smear stained with rapid Papanicolaou stain
- Air dried smear kept reserved for Z N staining.
Conclusion: FNAC is an important tool for clinical diagnosis which helps in planning the medical and surgical management of neck lesions. It can be confirmed with histopathological examination which is a gold standard for diagnosis.
References
- Mukul Patar, Kusum Borsaikia, Biraj K. Das, Anupam Hazarika. A clinicopatho-logical evaluation of cervical lymphadeno-pathy in children (0-14 Years) By fine needle aspiration cytology and histopathological examination - A hospital based study. Natl J Otorhinolaryngol Head Neck Surg. 2014;2(11):12-14.
- Allhiser JN, McKnight TA, Shank JC. Lymphadenopathy in a family practice. J Fam Pract. 1981;12(1):27-32.
- Steel BL, Schwartz MR, Ramzy I. Fine needle aspiration biopsy in the diagnosis of lymphadenopathy in 1,103 patients: role, limitations, an analysis of diagnostic pitfalls. Acta Cytol. 1995;39(1):76-81.
- Ghartimagar D, Ghosh A, Ranabhat S, Shrestha MK, Narasimhan R, Talwar OP. Utility of fine needle aspiration cytology in metastatic lymph nodes. J Pathol Nepal. 2011;1(2):92-95.
- Saleh H, Masood S. value of ancillary studies in fine needle aspiration biopsy. Diagn Cytopathol. 1995;13(4):310-5.
- McAdams HP, Gonshal IAG. Diagnosis of Tuberculosis. J Indian Med Assoc. 2000;98(3):57-61.
- Kumar RK. Tuberculosis lymphadenitis in children, role of fine needle aspiration cytology. J Assoc Physic India. 1999;47 (10):976-97.
- Bezabih M, Mariam DW, Selassie SG. Fine needle aspiration cytology of suspected tuberculous lymphadenitis. Cytopathology. 2002;13(5):284-290.
- Ahmad T, Naeem M, Ahmad S, Samad A, Nasir A. Fine needle aspiration cytology (FNAC) and neck swellings in the surgical outpatient. J Ayub Med Coll Abbottabad. 2008;20(3):30-2.
- Baji SN, Anand V, Sharma R, Deore KS, Chokshi M.. Analysis of FNAC of cervical lymph nodes: experience over a two years period. Int J Med Sci Public Health. 2014;3(5):607-9.
- Frable WJ. Fine-needle aspiration biopsy: a review. Hum Pathol. 1983;14(1):9-28.
- Volmar KE, Singh HK, Gong JZ. The advantages and limitations of the role of core needle and fine needle aspiration biopsy of lymph nodes in the modern era. Hodgkin and non-Hodgkin lymphomas and metastatic disease. Pathol Case Rev. 2007;12(1):10-26.
- Hirachand S, Lakhey M, Akhter J, Thapa B. Evaluation of fine needle aspiration cytology of lymph nodes in Kathmandu Medical College, Teaching hospital. Kathmandu Univ Med J. 2009;7(26):139-142.
- Vokes EE, Weichselbaum RR, Lippman SM. Head and neck cancer. N Engl J Med. 1993;328(3):185-194.
- A Clinico -pathological study of cervical lymph nodes ;Gaurav Batni, Sushil Gaur, O.N. Sinha, Siddhant Priya Agarwal and Abhinav Srivastava; Indian J Otolaryngol Head Neck Surg.2016 Dec; 68 (4) :508 -510
- Role of Fine needle aspiration cytology (FNAC) as a diagnostic tool in Pediatric Head and Neck Lymphadenopathy ;OA Silas , OO lge , AA Adoga, LT Nimkur, and Ol Ajetunmobi; J Otol Rhinol. 2015 Feb; 4(1):10.4172/2324-8785.1000211
- Loke YW. Lymphoepitheliomas of the cervical lymph nodes. Br J Cancer. 1965;19(3):482-5.
- Mathiot C, Decaudin D, Klijanienko J, Couturier J, Salomon A, Dumont J, et al. Fine-needle aspiration cytologic combined with flow cytometry immunophenotyping is a rapid and accurate approach for the evaluation of suspicious lymphoid lesions. Diagn Cytopathol. 2006;34(7):472-8.