Title: A study to evaluate the short term prognostic significance of HsCRP in acute coronary syndrome during hospital stay
Authors: Dr Saurabh Singh Tomar, Dr Manisha Chauhan
DOI: https://dx.doi.org/10.18535/jmscr/v7i1.185
Abstract
Introduction: The present study was designed to evaluate the serum concentration of HsCRP in acute coronary syndrome, its association with subsequent consequences to assess the short term
prognostic significance.
Objective: To evaluate the short term prognostic significance of HsCRP in acute coronary syndrome during hospital stay.
Methodology: Study Design: Case Control Observational Study.
Study Duration: 21 July 2017 to 21 March 2018.
Results: The prognosis of the patient with acute coronary syndrome depends upon the elevated value of HsCRP.
Conclusion: Very high HsCRP level, a potent independent predictor of poor prognosis in patients with acute myocardial infarction.
References
- Srinath Reddy K, Shah B, Varghese C, Ramadoss A: Responding to the threat of chronic diseases in Lancet 2005, 366(9498):1744-9.
- Peter Libby Treatment and prevention of atherosclerosis Harrison’s Principles of Internal Medicine 16th Edition Kasper, Braunwald, Fauci, Hauser, Longo, Jameson. McGraw Hill 2005.
- Lalchandani A, Dig Vijay T , Saxena SK et al. Blood levels of Myeloperoxidase, Creactive protein and Troponin I as prognostic marker in acute coronary Indian Heart J 2005;57:411.
- Liuzzo, L.M. Biasucci, J.R. Gallimore, Grillo R L, Rebuzzi A.G, Pepys M.B., Maseri A, The prognostic value of C-reactive protein and serum amyloid a protein in severe unstable angina. N Engl J Med 331 (1994), pp. 417-424.
- Honarmand H, Mirzajani E, Rahbar-Taromsari M, Saadat F et The relationship and diagnostic value of CRP and HsCRP for myocardial infarction, African Journal of Microbiology, 2011; 5 : 3215-3219
- Lindahl, H. Toss, A. Siegbahn, P. Venge and L. Wallentin, Markers of myocardial damage and inflammation in relation to long-term mortality in unstable coronary artery disease. FRISC Study Group: Fragmin during instability in coronary artery disease. N Engl J Med 343 (2000), pp. 1139-1147.
- Ramon Arroy, Espliguero et al. C-reactive protein evaluation and disease activity in patients with coronary artery disease. Europian Heart Journal, 2004;25: 401-408.
- Benjamin M Scirica et al. Clinical application of C-reactive protein across the spectrum of acute coronary syndromes. Clinical Chemistry, 2007; 53: pg1800-1807.