Title: A comparative study between intravenous propofol and an equipotent dose of thiopentone for the incidence of sore throat after Laryngeal Mask Airway (LMA) insertion
Authors: Subrata Kumar Mandal, Moumita Ghosh Nandi, Shantanu Ghosh, Manoj Kumar Ray
DOI: https://dx.doi.org/10.18535/jmscr/v7i1.157
Abstract
Introduction: The LMA (Laryngeal Mask Airway) is an excellent alternative method offering advantages of endotracheal intubation while avoiding the deleterious effects of succinylcholine. The present study was designed to draw a comparison as to which of the two induction agents, propofol and thiopentone sodium, caused less incidence of post-operative sore throat (POST) after LMA insertion.
Materials and Methods: Three hundred patients of either sex, ASA 1 and 2, aged 18 to 50 years undergoing minor elective surgeries under general anaesthesia were enrolled in this prospective, randomized, double blind study. Following premedication with midazolam (0.04 mg/kg) and fentanyl (1.5 μg/kg), patients were randomly allocated to be induced with propofol 2 mg/kg (group A, n=140) or thiopentone sodium 5 mg/kg (group B, n=140).
Results: The incidence of POST was statistically significantly greater in group B as compared to group A (p<0.05)
Conclusion: Propofol (2mg/kg) is a superior induction agent than thiopentone sodium (5mg/kg) for facilitating LMA insertion with lesser incidence of post-operative sore throat (POST).
Keywords: airway, laryngeal, mask, propofol, thiopentone, post-operative sore throat.
References
- Bahk, Jae-Hyon , Sung, Joohon, Jang , In-Jin. A comparison of Ketamine and Lidocaine Spray with Propofolfor the insertion of Laryngeal Mask Airway in children: A Double-Blinded Randomized Trial. Anaesth & Analg 2002;95:1586-9
- Jae-Hyon Bahk, Soung-Moon Han, Seong-Deok Kim . Management of difficult airways with a laryngeal mask airway under propofolanaesthesia. Pediatric anesthesia, 9:163-166 doi:10.1046/j.1460-9592.1999.9220305.x
- Zimmert M, Zwirner P, Kruse E, Braun U. Effects on vocal function and incidence of laryngeal disorder when using a laryngeal mask airway in comparison with an endotracheal intubation. Eur J Anaesthesiol 1999;16:511-5.
- Higgins PP, Chung F Mezei G. Postoperative sore throat after ambulatory surgery. Br J Anaesth 2002;88:582-4.
- Rieger A, Brunne B, Hass I, Brummer G, Spies C, Striebel HW, et al. Laryngo-pharyngeal complaints following laryngeal mask airway and endotracheal intubation. J Clin Anesth1997;9:42-7.
- Scanlon P, Carey M, Power M, Kirby F. Patient response to laryngeal mask insertion after induction of anaesthesia with propofol or thiopentone. Can J Anaesth 1993;40:816-8.
- Blake DW, Dawson P, Donnan G, Bjorksten A. Propofol induction for laryngeal mask airway insertion: dose requirement and cardiorespiratory effects. Anaesth Intensive Care 1992; 20: 479-83.
- Mc Hardy, FE Chung F. Postoperative sore throat: cause, prevention and treatment. Anesthesia 1999;54:444-53.
- Biro P, Seifert B, Pasch T. Complaints of sore throat after tracheal intubation: a prospective evaluation. European Journal of Anaesthesiology. 2005;22:307-11.