Obesity is a condition where BMI is ≥30kg/m².Obesity is seen to raise alarmingly due to the imbalance between the calorie intake and calorie expenditure. USA, China, India, Brazil are among the top 10 obese countries as of 2017. Obesity is caused due to physical, environmental and psychological factors affecting the body. Risk factors include changes in lifestyle, urbanisation which led to decrease in physical activity. Hypertrophic and Hyperplastic obesity are the two types of obesity patterns. Pathophysiology of obesity is characterised by the chronic and low-grade inflammation of an adipocytes due to the activation of inflammatory signalling pathway. Body Mass Index, waist-to-hip circumference ratio, waist circumference are the diagnostic parameters of obesity. Obesity can be treated initially with non-pharmacological treatment where diet restriction, regular physical activity and lifestyle modifications can be done. Pharmacological treatment includes use of appetite suppressants and lipase inhibitors class of drugs. Pharmacist can play a vital role in educating people and creating awareness about complications of obesity.

Keywords:  Obesity, Non-pharmacological treatment, macrophages, Appetite suppressants.

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Dr P. Kishore

Head, Department of Pharmacy Practice, Care College of Pharmacy, Oglapur (v), Damera (m), Warangal Rural, Telangana, India – 506006

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