Title: Stress hyperglycemia affecting clinical outcome in ischemic stroke patients
Authors: Dr Sweta Jadav, Dr Nivedita D. Moulick
DOI: https://dx.doi.org/10.18535/jmscr/v6i11.111
Abstract
Introduction: Hyperglycemia is common in the early phase of stroke. The present study was aimed to assess the effect of stress hyperglycemia on the functional outcome in patients with ischemic stroke patients admitted to our indoor wards.
Methodology: This prospective study was conducted in the Department of Medicine, DY Patil School of Medicine, Navi Mumbai from June 2017 till June 2018 of patients who were admitted with the diagnosis of ischemic stroke. Stress hyperglemia was defined as fasting serum glucose levels at the first day after admission ≥126 mg/dl in patients without diabetes mellitus. Information regarding the demography, anthropometry, risk factors and blood sugar were noted. The severity of stroke was assessed with the National Institutes of Health Stroke Scale (NIHSS) and clinical outcome was assessed using the modified Rankin scale (mRS) at discharge.
Results: During the study period, a total of 106 patients were included and were classified as normoglycemic, stress hyperglycemic and diabetic. The mean age and gender distribution of the patients in all the three groups was similar. After 3 months, the NIHSS was significantly higher among patients with stress hyperglycemia as compared to those with normoglycemia. Further, asignificantly higher proportion of patients with stress hyperglycemia had a poor outcome (according to mRS) as compared to normoglycemics and similar to those with diabetics.
Conclusions: Ischemic stroke patients with stress hyperglycemia had worse clinical and functional outcome over a short-term follow up period. at 3rd month of follow-up.
Keywords: Stress hyperglycemia; Diabetes mellitus; Ischemic stroke; Outcome.
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