COPD has a systemic inflammatory effect which extends beyond the pulmonary system resulting in a state of persistent low-grade systemic inflammation and this inflammation has been proposed as a key element in the association of COPD and CVD. Recently there has been growing attention given to the relationship between RDW and cardiovascular disorders, such as heart failure and coronary artery disease. The present study is conducted to see the relationship between RDW (red cell distribution width) in the relationship with right ventricle diastolic dysfunction in COPD patients. An Observational study conducted at R L Jalappa Hospital Kolar from January to June 2018 which included 98 patients. There is a statistically significant difference were observed in relationship to RDW and with parameters RV basal diameter, RV systolic pressure, RV wall thickness, RV mid cavity diameter, RV longitudinal diameter, Tricuspid E/A, Tricuspid S, Tricuspid e’,’ Tricuspid e’/a’,. And Tricuspid E/e’, S velocity and TAPSE except for Tricuspid E' and Tricuspid A'.26 members had RV Diastolic Dysfunction with RDW > 14.5 whereas only 4 members with RDW <14.5 and this is statistically significant. (Chi-square value of 37.6).The present study troughed some light that there might be a relationship between the increased level of RDW and RV diastolic dysfunction in COPD patients.

Keywords: COPD, CVD, RDW, Kolar, Karnataka.

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Tameem Imran

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