Title: Clinical Spectrum of Herpes Simplex Keratitis in Patients Attending various Health Institutions in North India
Authors: Dr Mohd Yousuf, Dr Mymoona Akhter, Dr Sajad
DOI: https://dx.doi.org/10.18535/jmscr/v6i11.25
Abstract
Introduction: Herpes simplex virus is responsible for numerous ocular diseases, the most common of which is herpetic stromal keratitis. The inflammatory response can lead to decreased corneal sensation, scarring, and blindness. So accurate diagnosis is necessary for proper treatment, in order to prevent serious consequences.
Methodology: This was a retrospective study documenting the clinical profile and outcome of herpetic keratitis treated in a hospital in North Indian State.
Results: An aggregate of 200 patients were determined to have herpetic keratitis. Most common presentation was dendritic ulcer, followed by stromal keratitis and geographical ulcer. Most frequent associated ocular lesion with keratitis was conjunctivitis followed by uveitis and lid involvement. Among 200 cases, 120 cases (60%) were males & 80 (40%) were females. Right eye was involved in 120 (60%) and left eye in 80 cases (40%). The age distribution and majority of Patients 72(36%) are in the age group of 30-40. Visual acuity was grossly reduced <or = 6/60 in majority of patients with stromal disease (93.8%) while majority of patients with epithelial disease (88.89%) had visual acuity > 6/60. 57 (63.3%) had complete resolution in ist week & rest 33(36.7%) took 2 weeks for complete resolution. 64.5% had complete resolution after treatment & only 5% had visually significant residual disease.
Keywords: cornea; herpes simplex virus; herpetic stromal keratitis.
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