Pre-diabetes (comprise of IFG and IGT) is the state that occurs when a person's blood glucose levels are higher than normal but not high enough for a diagnosis of diabetes. The terms IFG and IGT refer to an intermediate metabolic stage between normal glucose and diabetes.

The cross-sectional study was carried out in various locations of Telangana. The Researcher followed American Diabetic Association (ADA) criteria for defining the IFG and IGT. 1650 eligible subjects were selected for the study. Laboratory Investigations were done on subjects related to Fasting blood glucose and 2 h after Blood Glucose. Anthropometric Measurements also done to know BMI and Waist/Hip Ratio (WHR) on subjects.

The data was analyzed by using Chi square test using SAS version 8.2.Demographic background and baseline data was presented descriptively. All continuous variables like height, weight and laboratory data was represented by mean +SD (Standard Deviation).

Overall prevalence rate of IFG in Telangana state is around 2.75% and IGT is around 6.11%.The data proves that BMI and WHR are highly significant statistically in IFG population. The result proves that IFG population is more prone to develop obesity. This data proves that BMI and WHR is highly significant statistically in IGT population. It is true that IGT population is more prone to develop obesity.

Pre diabetes can prevent or delay the development of type 2 diabetes by through changes to their lifestyle that include modest weight loss, regular exercise and proper diet.

Keywords: Assessment, pre-diabetes, Impaired fasting glucose(IFG), Impaired glucose tolerance (IGT).

1. Charles, M. A., Fontboune, A., Thibult, N., Warnet, J. M., Rosselin, G. E. & Eschwege, E. Risk factors for NIDDM in white population. Paris prospective study. Diabetes 40, 796-799; 1991.
2. Fernando Guerrero-Romero, Martha Rodrõ Âguez-MoraÂn: Journal of Diabetes and its complications; 15, 34-37;2001
3. Brunzell, J. D., Robertson, R. P., Lerner, R. L., Hazzard, W. R., Ensink, J. W., Biewrman, E. L., & Porte, D. Jr: Relationship between fasting plasma glucose levels and insulin secretion during intravenous glucose tolerance test. J Clin Endocrinol Metab 42, 222- 229; 1976.
4. Gomez-Perez, F. J., Aguilar-Salinas, J. C., Lopez-Alveranga, J. C., Perez-Jauregui, J., Guillen-Pineda, L. E., & Rull, J. A: Lack of agreement between the World Health Organization category of impaired glucose tolerance and the American Diabetes Association category of impaired fasting glucose. Diabetes Care 21. 1886-1888; 1998.
5. Gimeno, S. G. A., Ferreira, S., Franco, L., & Iunes, M:Comparison of glucose tolerance categories according to World Health Organization and American Diabetes Association diagnostic criteria in a population based study in Brazil. Diabetes Care 21, 1889-1892; 1998.
6. Vegt, F., Dekker, J. M., Stehouwer, C., Nijpels, G., Bouter, L., & Heine, R: The 1997 American Diabetes Association criteria versus the 1985 World Health Organization criteria for the diagnosis of abnormal glucose tolerance. Diabetes Care 21. 1686- 1690; 1998.
7. Guerrero-Romero, F., Rodriguez-Moran, M., & Alvarado-Ruiz, R:Concordance between the 1997 fasting ADA criteria and the WHO criteria in healthy Mexican subjects. Diabetes Care 22. 527; 1999 (letter).
8. Lal Somani, B., Bangar, S. S., & Bhalwar, R: American Diabetes Association criteria for diabetes diagnosis. Diabetes Care. 22,366; 1999 (letter).
9. American Diabetes Association website; www.ada.org. As per the last assessed on May 2007.
10. Delahanty LM, Grant RW, Wittenberg E,Bosch JL, Wexler DJ, Cagliero E, Meigs JB: Association of diabetes-related emotionaldistress with diabetes treatment in primary care patients with Type 2 diabetes.Diabet Med.24:48–54;2007.
11. Carey, D, Jenkins A, Campbell L, Freund J, Chisholm D:Abdominal fat and insulin resistance in normal and overweight women: direct measurements reveal a strong relationship in subjects at both low and high risk of NIDDM. Diabetes. 45:633– 638. 1996
12. Pratley RE,Weyer C: aCurr Diab Rep. Jun; 2(3):242-248. 2002.
13. Shobha S.Rao,Philip Disraeli and Tamar McGregor: Impaired Glucose Tolerance and Impaired Fasting Glucose, Am Fam Physician, 69, 1961-1968, 1971-1972; 2004.
14. Mohan: Why Indians are more prone to Diabetes? Journal of Physicians of India (JAPI) Vol.52, June 2004.
15. Deepa M, Pradeepa R, Rema M, Mohan A, Deepa R, Shanthiarani S, et al: The Chennai Urban Rural Epidemiology Study (CURES) study design and Methodology. Urban Component (CURES-1),JAPI Vol.51,863-870,September 2003.
16. Knowler WC, Barrett-Connor E, Fowler SE, et al.Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin. N Engl J Med.;346:393– 403; 2002.
17. Vaag A, Henriksen JE, Beck-Nielsen H:Decreased insulin activation of glycogen synthase in skeletal muscles of young non-obese Caucasian first degree relatives of patients with non-insulin dependent diabetes mellitus. J Clin Invest. 89:782–788. 1992.

Madan Mohan Laddunuri