Title: The incidence of differentiated carcinoma thyroid as histopathologic surprise in FNAC proved benign thyroid nodules
Authors: Dr Nandagopal Vasudevan, Dr Premlal A.P, Dr Balagopal K
DOI: https://dx.doi.org/10.18535/jmscr/v6i10.130
Abstract
Background: The main role of fine needle aspiration cytology (FNAC) lies in differentiating between a malignant and benign thyroid nodule. It greatly influences the treatment decision. The current study was undertaken to evaluate the cytology-histopathology correlation.
Materials and Methods: This is a retrospective study comparing cytology and corresponding histopathology report in 100 thyroid cases. The statistical analysis included false positive rate, false negative rate, sensitivity, specificity, positive predictive value, negative predictive value and accuracy.
Results: The sensitivity of FNAC is 92% in the present study and false negative occurred in 8% cases. The incidence of histopathologic surprise (as differentiated carcinoma thyroid) in nodular thyroid is 8%. FNAC is a very powerful tool in the Preoperative investigator benign nodular- thyroid with a sensitivity of 92%. Male: Female ratio in patients presenting with histologic surprise is 1:7. Age group which shows maximum chance for harbouring histologic surprise is between 25-30 years. Solitary nodular thyroid shows maximum false negative in FNAC followed by MNG.
Keywords: Cytology, FNAC, Thyroid, Thyroid cancer.
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