Title: Bilirubin, Uric acid level changes in Metabolic syndrome and Diabetes Mellitus: A Comparative study

Authors: Dr Sai Ravi Kiran.B, Dr MD.Rafi, Dr E. Prabhakar Reddy

 DOI:  https://dx.doi.org/10.18535/jmscr/v6i10.48

Abstract

Metabolic  syndrome (MetS)  represents  a  cluster  of  several  risk  factors  that  includes  dyslipidemia,  obesity,  increased  blood pressure and hyperglycemia, proinflammatory state, prothrombiotic state. Diabetes Mellitus (DM) is chronic hyperglycemia which includes most common complications i.e. atherosclerosis, nerve damage, renal damage, retinopathy. Our aim is to evaluate Bilirubin and Uric acid in patients with MetS and DM controls. The study included 50 MetS patients, 50 diabetic patients and 50 Controls 5 ml of venous blood samples were collected from patients and controls. All the samples were collected overnight fasting of 12 hrs. Collected samples centrifuged under 2000 rpm for 20 min and after centrifugation of samples used for the determination of Cholesterol, Bilirubin and Uric acid. Blood glucose, Uric acid, Bilirubin significantly increased in diabetic patients comparing with Mets and Controls.

Keywords: Chronic hyperglycemia, Obesity, Atherosclerosis, Antioxidant acitivity.

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