Leiomyoma is the most common type of benign tumor of uterus and carry 70-80% of cumulative incidence in reproductive age group. Our study was conducted to analyse the clinicopathological correlation, spectrum of variants and secondary changes of leiomyoma of uterus. The clinical presentation, histological pattern and combination with other reproductive tract lesions were also studied. The time period was two years from September 2016 to August 2018. A total of 100 hysterectomy and myomectomy specimens received in pathology department of T.S. Misra Medical College, were included in the study. Most of the patients of leiomyoma were present in their reproductive age. Hyaline change and calcification are commonly seen in longstanding leiomyomas and are clinically asymptomatic. In our study the incidence remains highest in the child bearing age group. Intramural leiomyoma was present in highest number. The presence of proliferative phase of endomentrium, endometrial hyperplasia, adenomyosis and cystic ovaries indicated association of leiomyoma with high estrogen levels in the blood.

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Dr Poornima Mishra

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